[Hospitalization trends of neuropsychiatric disorders in a middle-income country].

Background: Neuropsychiatric disorders represent one of the first causes of disability worldwide. Recognizing the main causes for hospitalization may allow the implementation of interventions to prevent hospitalization and promote ambulatory care.

Objective: To describe the trends of mental disorders requiring hospitalization in a neuropsychiatric referral center of a middle-income country.

Deep-brain stimulation in treatment-resistant obsessive-compulsive disorder: Clinical and molecular neuroimaging correlation.

Introduction: Obsessive-compulsive disorder is defined by the presence of obsessions and compulsions that cause marked anxiety or distress and has been associated with a disruption in cortico-striato-thalamo-cortical circuitry. After treatment, around 50% of patients continue to experience incapacitating symptoms. Deep-brain stimulation has been shown to be an effective therapeutic alternative to regular treatment.