Publications by authors named "Luis F Olivera-Fragoso"
Nitric oxide regulates vascular adaptive mitochondrial dynamics.
Am J Physiol Heart Circ Physiol
June 2013
Article Synopsis
- Impaired endothelial nitric oxide synthase (eNOS) function and decreased nitric oxide (NO) production are linked to cardiovascular disease risk factors like diabetes and obesity, affecting mitochondrial health.
- Genetic eNOS deletion and short-term NOS inhibition in rodents led to reduced mitochondrial protein levels and disrupted fission/fusion processes in the aorta.
- The study highlights the importance of eNOS/NO in maintaining both baseline and adaptive mitochondrial biogenesis within blood vessels, which is crucial for cardiovascular health.