Publications by authors named "Luis Didier Gonzalez-Garcia"
Collateral Damage in the Placenta during Viral Infection in Pregnancy: A Possible Mechanism for Vertical Transmission and an Adverse Pregnancy Outcome.
Diseases
March 2024
Article Synopsis
- The placenta serves as a vital connection between the mother and developing fetus, offering protection, nutrient transport, and waste exchange.
- Some viruses possess the ability to invade the placenta, potentially causing harm like necrosis and complications for both the fetus and mother.
- Understanding these viral mechanisms can enhance research in maternal-fetal health and inform new therapeutic approaches and biomarkers for fetal development.
Respiratory syncytial virus (RSV) is most commonly associated with upper respiratory tract infections during childhood. The lipid composition of cells and lipogenic enzymes play an important role in RSV infection. There are controversial data about whether lipid biosynthesis regulators such as AMP-activated protein kinase (AMPK) are deregulated by RSV.
View Article and Find Full Text PDFThe placenta is a highly specialized organ that is formed during human gestation for conferring protection and generating an optimal microenvironment to maintain the equilibrium between immunological and biochemical factors for fetal development. Diverse pathogens, including viruses, can infect several cellular components of the placenta, such as trophoblasts, syncytiotrophoblasts and other hematopoietic cells. Viral infections during pregnancy have been associated with fetal malformation and pregnancy complications such as preterm labor.
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