Publications by authors named "Luis Carlos Pinzon Herrera"
Soft Matter
November 2024
Article Synopsis
- Collagen plays a crucial role in the extracellular matrix (ECM) and its orientation is essential for replicating cellular environments, but creating large-scale aligned collagen structures is challenging.
- Type I collagen can self-assemble into liquid crystalline mesophases at acid conditions and high concentrations, which aids in aligning collagen on substrates, but processing these high concentrations presents difficulties.
- This study successfully achieves centimeter-scale alignment of collagen on glass substrates at lower concentrations, and extends this alignment to 3-D hydrogels, showing that the alignment influences the orientation of human Schwann cells, with a model estimating the magnetic field needed for future studies on collagen alignment.
