Publications by authors named "Luis Basbus"

Article Synopsis
  • The CheckMate-743 trial showed that nivolumab plus ipilimumab improves overall survival in patients with unresectable pleural mesothelioma compared to chemotherapy, but lacked representation of Latin American patients.
  • A retrospective study evaluated this treatment's effectiveness and safety in 96 LATAM patients, focusing on their demographic and clinical characteristics, with a median follow-up of 24.1 months.
  • Results indicated median progression-free survival of 8 months and overall survival of 22 months, confirming treatment benefits similar to other findings, with manageable adverse events reported.
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Introduction: Lung cancer remains a leading cause of cancer-related mortality worldwide. Detecting mutations in the epidermal growth factor receptor (EGFR) is crucial for treatment selection due to the response to tyrosine kinase inhibitors (TKIs) in these patients.

Objective: Describe the prevalence and identify factors associated with survival in stage IV lung cancer patients harboring EGFR mutations in a real-world setting.

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Article Synopsis
  • Passive immunotherapy, specifically using hyperimmune equine serum, was evaluated for its effectiveness in treating patients with COVID-19 pneumonia who were not hypoxemic and treated as outpatients.
  • A study conducted at a hospital in Argentina included 151 patients from May to August 2021, comparing those receiving equine serum and standard treatment with those on just standard treatment.
  • Results showed no significant differences in hospitalization rates or mortality between the two groups, indicating that hyperimmune equine serum may not provide additional clinical benefits in this setting.
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Introduction: Between 5-10% of patients who undergo curative surgery for colorectal cancer (CRC) will present recurrence of their disease on the lungs. Surgical treatment of pulmonary metastases (PM) has gained popularity over the years, different publications report an overall survival rate at 5 years of between 30% and 60%. We present a review of patients with PM resections of CRC treated in a single center in Argentina.

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In December 2019, a new coronavirus was identified as the cause of an outbreak of pneumonia and respiratory distress in Wuhan, China. It was declared pandemic in March 2020. It is important to know predictors of poor outcomes in order to optimize the strategies of care in newly diagnosed patients.

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