A novel multi-hazard risk assessment framework for coastal cities under climate change.

Coastal cities, as centres of human habitation, economic activity and biodiversity, are confronting the ever-escalating challenges posed by climate change. In this work, a novel Multi-Hazard Risk Assessment framework is presented with the focus on Coastal City Living Labs. The methodology provides a comprehensive assessment of climate-related hazards, including sea-level rise, coastal flooding, coastal erosion, land flooding, heavy precipitation, extreme temperatures, heatwaves, cold spells, landslides and strong winds.

Phase boundaries, nucleation rates and speed of crystal growth of the water-to-ice transition under an electric field: a simulation study.

We investigate with computer simulations the effect of applying an electric field on the water-to-ice transition. We use a combination of state-of-the-art simulation techniques to obtain phase boundaries and crystal growth rates (direct coexistence), nucleation rates (seeding) and interfacial free energies (seeding and mold integration). First, we consider ice Ih, the most stable polymorph in the absence of a field.

A novel resistance mechanism to triclosan that suggests horizontal gene transfer and demonstrates a potential selective pressure for reduced biocide susceptibility in clinical strains of Staphylococcus aureus.

The widely used biocide triclosan selectively targets FabI, the NADH-dependent trans-2-enoyl-acyl carrier protein reductase, which is an important target for narrow-spectrum antimicrobial drug development. In relation to the growing concern about biocide resistance, we compared in vitro mutants and clinical isolates of Staphylococcus aureus with reduced triclosan susceptibility. Clinical isolates of S.