Publications by authors named "Luis Antonio Dubey-Ortega"
Background: Iron overload can affect cardiac structure and function by the production of free radicals in addition to iron deposits in heart muscle. The purpose of this study was to compare traditional and non-traditional cardiovascular risk factors (CVRF) in children and adolescents on renal replacement with and without iron overload. Also, we evaluated the relationships between iron overload and left ventricular mass (LVM).
View Article and Find Full Text PDFRecent studies considered that an increase in sympathetic activity (SA) may be responsible for left ventricular hypertrophy (LVH). Before and after renal transplantation (RT), we evaluated changes on left ventricular mass (LVM) and SA in 40 end-stage renal disease patients between 8 and 35 years old. Hypertension (95.
View Article and Find Full Text PDFArticle Synopsis
- A randomized clinical trial in pediatric patients with end-stage renal failure compared maintenance iron therapy based on serum ferritin levels to intermittent iron doses; the study group received lower monthly iron doses.
- After 4 months, the maintenance group had significant increases in ferritin levels (66 microg/l) compared to the intermittent group (334 microg/l), showing better control of iron levels.
- The maintenance therapy was more effective, achieving stabilization and increasing hemoglobin levels while reducing the risk of iron overload (19% vs. 70%).