Publications by authors named "Luis Antonio Baffile Leoni"
Post-Partum Depression Lactating Rat Model for Evaluating Ketamine's Safety as a Pharmacotherapeutic Treatment: Roles in Cardiac and Urinary Function.
André Rinaldi Fukushima Pedro Enrique Navas-Suárez Juliana Weckx Peña Muñoz Esther Lopes Ricci Luís Antônio Baffile Leoni
J Cardiovasc Dev Dis
September 2022
Article Synopsis
- Depression, particularly postpartum depression (PPD), impacts about one in seven women globally and can affect the mother-child bond and the newborn's development.
- This study focuses on the effects of ketamine as a treatment for PPD in lactating rat mothers, evaluating its safety and effects on the cardiovascular system and behavior during maternal separation stress.
- Results indicate that ketamine could be a safe option for treating postpartum depression without causing harm to the cardiovascular or urinary systems of lactating mothers.
Development, Optimization, and Validation of Forensic Analytical Method for Quantification of Anticholinesterase Pesticides in Biological Matrices from Suspected Cases of Animal Poisoning.
André Rinaldi Fukushima Juliana Weckx Peña-Muñoz Luís Antônio Baffile Leoni Maria Aparecida Nicoletti Glaucio Monteiro Ferreira
Toxics
May 2022
Anticholinesterase pesticides are a main cause of the intentional or accidental poisoning of animals. Anticholinesterases include several substances that cause the overstimulation of both central and peripheral acetylcholine-dependent neurotransmission. Forensic analyses of poisoning cases require high levels of expertise, are costly, and often do not provide reliable quantitative information for unambiguous conclusions.
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