Background: Ocular trauma is one of the most important causes of ocular morbidity and inadequate visual acuity in developed and developing countries. In some countries, eye trauma is the leading cause of monocular blindness. Studies conducted in developing countries like Colombia suggest that there is a lack of awareness of preventive measures.
View Article and Find Full Text PDFBMJ Open
May 2022
Purpose: Preterm birth (PTB) is a public health issue. Interventions to prolong the length of gestation have not achieved the expected results, as the selection of population at risk of PTB is still a challenge. Cervical length (CL) is the most accepted biomarker, however in the best scenario the CL identifies half of the patients.
View Article and Find Full Text PDFCongenital heart defects have been associated with adverse neurodevelopmental outcomes due to factors that result in a hypoxic-ischemic cerebral cumulative effect. We present a pair of fraternal twins: the first twin was healthy, and the second was born with a complex congenital heart defect (CCHD). They were followed for growth and neurodevelopmental outcomes to determine the comparative effect of exposure to a CCHD.
View Article and Find Full Text PDFAn epidemic of Zika virus (ZIKV) infection began in Colombia in October 2015. Previous studies have identified a cause-effect relationship between fetal exposure to the ZIKV and the development of microcephaly and other central nervous system (CNS) anomalies with variable degrees of neurodevelopmental delay. Less is known about the neurodevelopmental outcome of infants without CNS anomalies born to symptomatic ZIKV RT-PCR-positive women.
View Article and Find Full Text PDFActa Obstet Gynecol Scand
February 2022
Introduction: In October 2015, an epidemic of Zika began in Colombia's geographic areas with a high population of mosquitoes of the genus Aedes. We aimed to describe the fetal brain ultrasound findings in pregnant women with active symptoms or a history of symptoms suggestive of Zika virus (ZIKV) infection.
Material And Methods: Eligible pregnant women were tested with reverse transcriptase-polymerase chain reaction (RT-PCR) for ZIKV and followed prospectively using detailed anatomic ultrasound and transvaginal neurosonography to detect structural anomalies of the fetal central nervous system (CNS).
Objective: To design and validate a scale to evaluate the quality of life in children and adolescents with epilepsy.
Methods: Scale validation, multicentered, three-phase study. We did a literature review for the construction of the instrument, and a validation of appearance, construct, criterion, and reproducibility.
Pentraxin-3 has been reported as a promising biomarker of pre-eclampsia and its severity; however, available studies have small sample sizes, and analyses are not always adjusted for confounders. The aim of this study is to establish the strength of the association between maternal Pentraxin-3 level and pre-eclampsia or HELLP syndrome. It was a case-control study.
View Article and Find Full Text PDFBackground: Conventional serum tumor markers (CSTM) are widely used for monitoring patients with cancer. However, their usefulness as a diagnostic tool is controversial in primary or metastatic liver cancer (PMLC).
Aim: To evaluate the diagnostic performance of the most commonly requested CSTM in the diagnostic approach of PMLC.
Introduction: In preterm newborn, problems with the interpretation of 17-OHP may occur.
Objective: Evaluate 17-OHP values in healthy preterm newborns until they reach the corrected gestational age.
Methods: Longitudinal study of 36 preterm infants with 17-OHP evaluation using ELISA from heel blood from 3 to 5 days and thereafter every 2 weeks until the corrected gestational age.
Bol Med Hosp Infant Mex
October 2015
Introduction: Continuous positive airway pressure (CPAP) is useful in low birth weight infants with respiratory distress, but it is not known if it is a better alternative to mechanical ventilation after early pulmonary surfactant administration.
Objective: To compare the incidence of adverse events in 28 to 32-week newborns with respiratory distress managed with mechanical ventilation or CPAP after early surfactant administration.
Materials And Methods: In total, 176 newborns were treated with CPAP and 147 with mechanical ventilation, all with Apgar scores >3 at five minutes and without apnea.
Preeclampsia affects between 4% to 8% of all human pregnancies. It compromised both mothers and offspring beyond perinatal period. This is the second of two papers devoted to show the available evidence about the effect of preeclampsia on offsprings beyond perinatal period from cohort studies, some over 60-years follow-up.
View Article and Find Full Text PDFPreeclampsia affects between 4 to 8% of all human pregnancies. It compromised both mothers and offspring beyond perinatal period. This is the first o two papers related whit this phenomenon and shows the available evidence about the effect of preeclampsia over the preeclamptic offspring from cohort studies.
View Article and Find Full Text PDFObjective: To evaluate the relationship between breastfeeding and the development of allergic diseases (AD).
Design: A cases-controls study.
Setting: Santander University Hospital, Bucaramanga, Colombia, South America.
This study aimed to establish the prevalence of daily cigarette smoking (DCS) and its gender correlated factors in high-school attending adolescents from Bucaramanga, Colombia. A random cluster sample was surveyed (N = 2291). The previous month DCS prevalence was 11.
View Article and Find Full Text PDFObjective: To determine the internal consistency, factorial structure, reproducibility and validity of criterion of the Leyton Obsessional Inventory in children and adolescents.
Design: Study of validation with probabilistic sampling.
Setting: Secondary schools in Bucaramanga, Colombia.
Various studies have reported an important association between depressive symptoms and alcohol abuse. However, the topic had not been investigated in Colombian students. This study focused on the association between depressive symptoms and alcohol abuse among high school students in Bucaramanga, Colombia.
View Article and Find Full Text PDFAn anonymous, self-administered and voluntary survey was performed on medical students participating in the 17th International Scientific Meeting of the Latin American Federation of Scientific Societies of Medical Students, which took place in Lima, on October 2002. A total of 198 students responded, 150 of them were Peruvian. The results showed that 46.
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