Publications by authors named "Luis Alberto Bautista-Herrera"

Article Synopsis
  • - Skin cancer is very common, with cutaneous squamous cell carcinoma (cSCC) making up 20% of non-melanoma skin cancers, and a specific gene plays an important role in cancer development.
  • - A study involving 211 cSCC patients and 290 control group individuals examined gene variants through a technique called qPCR, but found no significant links between certain gene variants and cSCC risk.
  • - While some variants showed potential effects, this study suggests that larger groups are needed to better understand the impact of rare genetic variants on cSCC risk in the Mexican population.
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Background: Functional variants -173 G > C (rs755622) and -794CATT (rs5844572) MIF gene have been associated with the risk in several types of cancer, as well as with the increase of soluble levels of MIF and TNFα. However, in previous studies contradictory and uncertain results have been presented on the implication of MIF polymorphisms with the association in cancer, specifically in breast cancer (BC). We investigated whether the variants are associated with the susceptibility to develop BC and the soluble levels of MIF and TNFα in women with BC from western Mexico.

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Breast cancer (BC) is a health problem worldwide; there is evidence that inflammatory cytokines are increased in BC. Macrophage migration inhibitory factor (MIF) has multiple effects on immune cells, inflammation and cancer. Besides, in previous studies, contradictory and uncertain results have been presented on the implication of Th17 cytokine profile in BC.

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