Publications by authors named "Luis A Perez-Arredondo"
Comment on Samara et al. Metformin Use Is Associated With Slowed Cognitive Decline and Reduced Incident Dementia in Older Adults With Type 2 Diabetes: The Sydney Memory and Ageing Study. Diabetes Care 2020;43:2691-2701.
Diabetes Care
April 2021
Nonalcoholic fatty liver disease (NAFLD) is a serious worldwide health problem, with an estimated global prevalence of 24%; it has a notable relationship with other metabolic disorders, like obesity and type 2 diabetes mellitus (T2DM). Nonalcoholic steatohepatitis (NASH) is one of the most important clinical entities of NAFLD, which is associated with an increased risk of progression to liver cirrhosis and hepatocellular carcinoma (HCC). Mexico is one of the countries with the highest prevalence of metabolic diseases; therefore, we sought to investigate the impact that these clinical entities have in the progression to advanced fibrosis in Mexican patients with NASH.
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- The study aimed to compare morning serum cortisol (MSC) levels with a 10 mg ACTH stimulation test for diagnosing adrenal insufficiency (AI) through a retrospective analysis of 306 eligible tests.
- The results showed that MSC had high diagnostic performance with area under the curve values of up to 0.925, along with good sensitivity (83.3%) and specificity (89.1%) for identifying AI.
- The findings suggest that MSC could serve as a first-step diagnostic test, potentially allowing for the avoidance of ACTH stimulation tests in nearly half the cases, warranting further research for confirmation.
Testicular cancer is the most common solid malignancy affecting males between the ages of 15 and 35. The symptomatology caused by this tumor varies according to the site of metastasis. We present the case of a 26-year-old male who arrived to the emergency department with hematemesis.
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