Strong Chiro-Optical Activity of Plasmonic Metasurfaces with Inverted Pyramid Arrays.

Chiral plasmonics has emerged as a powerful tool for manipulating light at the nanoscale with unprecedented control over light polarization. The advances in nanofabrication have led to the creation of nanostructures that support strong chiroptical responses. However, the complexity of the fabrication and the associated high costs remain major challenges in upscaling these architectures.

Chiral plasmonic superlattices from template-assisted assembly of achiral nanoparticles.

The creation of chiral plasmonic architectures combining templates with achiral plasmonic particles leads to strong chiroptical responses that can be finely tuned via the characteristics of the colloidal building blocks. Here we show how elastomeric molds, pre-patterned with a hexagonal array of triskelia motifs, can guide the assembly of ordinary noble metal colloids into chiral plasmonic architectures with strong dichroism values. Under normal incidence, the chiral arrays made with gold and silver colloids showed g-factors of 0.

Incidence of metabolic bone disease in neonates under 32 gestational weeks at the Hospital Universitario de Santander in Colombia.

Introduction: Metabolic bone disease of premature infants is a rare complication characterized by a lower mineral content in bone tissue.

Objective: To establish the incidence of metabolic bone disease in premature infants and to determine associated risk factors.

Materials And Method: We conducted a descriptive prospective cohort study for one year in all newborns under 32 gestational weeks, or 1,500 g, at the Hospital Universitario de Santander to determine the incidence of metabolic bone disease.

Fibroblast-Derived Lysyl Oxidase Increases Oxidative Phosphorylation and Stemness in Cholangiocarcinoma.

Background & Aims: Metabolic and transcriptional programs respond to extracellular matrix-derived cues in complex environments, such as the tumor microenvironment. Here, we demonstrate how lysyl oxidase (LOX), a known factor in collagen crosslinking, contributes to the development and progression of cholangiocarcinoma (CCA).

Methods: Transcriptomes of 209 human CCA tumors, 143 surrounding tissues, and single-cell data from 30 patients were analyzed.

High -Factor Plasmonic Surface Lattice Resonances in Colloidal Nanoparticle Arrays.

Surface lattice resonances (SLRs) sustained by ordered metal arrays are characterized by their narrow spectral features, remarkable quality factors, and the ability to tune their spectral properties based on the periodicity of the array. However, the majority of these structures are fabricated using classical lithographic processes or require postannealing steps at high temperatures to enhance the quality of the metal. These limitations hinder the widespread utilization of these periodic metal arrays in various applications.

Granular Disulfide-Crosslinked Hyaluronic Hydrogels: A Systematic Study of Reaction Conditions on Thiol Substitution and Injectability Parameters.

Granular polymer hydrogels based on dynamic covalent bonds are attracting a great deal of interest for the design of injectable biomaterials. Such materials generally exhibit shear-thinning behavior and properties of self-healing/recovery after the extrusion that can be modulated through the interactions between gel microparticles. Herein, bulk macro-hydrogels based on thiolated-hyaluronic acid were produced by disulphide bond formation using oxygen as oxidant at physiological conditions and gelation kinetics were monitored.

Critical Current Density in -Wave Hubbard Superconductors.

In this work, the Generalized Hubbard Model on a square lattice is applied to evaluate the electrical current density of high critical temperature -wave superconductors with a set of Hamiltonian parameters allowing them to reach critical temperatures close to 100 K. The appropriate set of Hamiltonian parameters permits us to apply our model to real materials, finding a good quantitative fit with important macroscopic superconducting properties such as the critical superconducting temperature (Tc) and the critical current density (Jc). We propose that much as in a dispersive medium, in which the velocity of electrons can be estimated by the gradient of the dispersion relation ∇ε(k), the electron velocity is proportional to ∇E(k) in the superconducting state (where E(k)=(ε(k)-μ)2+Δ2(k) is the dispersion relation of the quasiparticles, and is the electron wave vector).

Anisotropic thermoreflectance thermometry: A contactless frequency-domain thermoreflectance approach to study anisotropic thermal transport.

We developed a novel contactless frequency-domain thermoreflectance approach to study thermal transport, which is particularly convenient when thermally anisotropic materials are considered. The method is based on a line-shaped heater geometry, produced with a holographic diffractive optical element, instead of using a spot heater as in conventional thermoreflectance. The heater geometry is similar to the one used in the 3-omega method, however, keeping all the technical advantages offered by non-contact methodologies.

[Relationship between gestational obesity and adverse perinatal outcomes: A multicenter study].

Introduction: To identify the association between maternal obesity and perinatal adverse outcomes in a population from the Colombian northeast.

Patients And Method: Multicenter, prospective, transverse study with patients who consulted and completed their pregnancy at the Clinica Materno Infantil San Luis and Hospital Universitario de Santander, between January 2019 and March 2020. The nutritional status of the patients was classified according to the Rosso-Mardones curve and obese and normal- weight pregnant women were included.

Hyaluronic Acid Hydrogels Crosslinked in Physiological Conditions: Synthesis and Biomedical Applications.

Hyaluronic acid (HA) hydrogels display a wide variety of biomedical applications ranging from tissue engineering to drug vehiculization and controlled release. To date, most of the commercially available hyaluronic acid hydrogel formulations are produced under conditions that are not compatible with physiological ones. This review compiles the currently used approaches for the development of hyaluronic acid hydrogels under physiological/mild conditions.

Large-Scale Soft-Lithographic Patterning of Plasmonic Nanoparticles.

Micro- and nanoscale patterned monolayers of plasmonic nanoparticles were fabricated by combining concepts from colloidal chemistry, self-assembly, and subtractive soft lithography. Leveraging chemical interactions between the capping ligands of pre-synthesized gold colloids and a polydimethylsiloxane stamp, we demonstrated patterning gold nanoparticles over centimeter-scale areas with a variety of micro- and nanoscale geometries, including islands, lines, and chiral structures ( square spirals). By successfully achieving nanoscale manipulation over a wide range of substrates and patterns, we establish a powerful and straightforward strategy, nanoparticle chemical lift-off lithography (NP-CLL), for the economical and scalable fabrication of functional plasmonic materials with colloidal nanoparticles as building blocks, offering a transformative solution for designing next-generation plasmonic technologies.

Epidermolysis bullosa with pyloric atresia: Report of two cases in consecutive siblings.

Pyloric atresia is a rare digestive malformation. It represents about 1% of intestinal atresias and is associated with some other genetic or anatomical alteration in 55% of the cases. In 20% of them, it is associated with epidermolysis bullosa, which is described as an established syndrome with a bad prognosis.

Observation of second sound in a rapidly varying temperature field in Ge.

Second sound is known as the thermal transport regime where heat is carried by temperature waves. Its experimental observation was previously restricted to a small number of materials, usually in rather narrow temperature windows. We show that it is possible to overcome these limitations by driving the system with a rapidly varying temperature field.

In Situ Synthesis of Poly(butyl methacrylate) in Anodic Aluminum Oxide Nanoreactors by Radical Polymerization: A Comparative Kinetics Analysis by Differential Scanning Calorimetry and H-NMR.

In this work, we explore the ability to generate well-defined poly(butyl methacrylate) (PBMA) nanostructures by "in situ" polymerization of butyl methacrylate monomer (BMA). PBMA nanostructures of high and low aspect ratios have been successfully obtained through the free radical polymerization (FRP) of a BMA monomer in anodic aluminum oxide (AAO) nanoreactors of suitable size. A polymerization kinetics process has been followed by differential scanning calorimetry (DSC) and proton Nuclear Magnetic Resonance spectroscopy (H-NMR).

Highly Efficient Hybrid Ni/Nitrogenated Graphene Electrocatalysts for Hydrogen Evolution Reaction.

Two nickel/nitrogenated graphene hybrid electrodes ( and ) were synthesized, and their catalytic activity with respect to the hydrogen evolution reaction (HER) in alkaline media was analyzed. Incorporation of nitrogen to the carbon structure in graphene oxide (GO) or reduced GO (rGO) flakes in aqueous solutions was carried out based on two different configurations. particles were obtained by a hydrothermal method using ammonium hydroxide as the precursor, and particles were obtained by silanization (APTES functionalization) of GO sheets.

Band-gap engineering of halogenated silicon nanowires through molecular doping.

In this work, we address the effects of molecular doping on the electronic properties of fluorinated and chlorinated silicon nanowires (SiNWs), in comparison with those corresponding to hydrogen-passivated SiNWs. Adsorption of n-type dopant molecules on hydrogenated and halogenated SiNWs and their chemisorption energies, formation energies, and electronic band gap are studied by using density functional theory calculations. The results show that there are considerable charge transfers and strong covalent interactions between the dopant molecules and the SiNWs.

[Nasal CPAP versus mechanical ventilation in 28 to 32-week preterm infants with early surfactant administration].

Introduction: Continuous positive airway pressure (CPAP) is useful in low birth weight infants with respiratory distress, but it is not known if it is a better alternative to mechanical ventilation after early pulmonary surfactant administration.

Objective: To compare the incidence of adverse events in 28 to 32-week newborns with respiratory distress managed with mechanical ventilation or CPAP after early surfactant administration.

Materials And Methods: In total, 176 newborns were treated with CPAP and 147 with mechanical ventilation, all with Apgar scores >3 at five minutes and without apnea.

Plasmonic interactions: from molecular plasmonics and Fano resonances to ferroplasmons.

Plasmon interactions are a subject of great interest from both the technological as well as the fundamental points of view. In this Perspective, we outline the great variety of physical phenomena that are produced by the interactions of localized surface plasmon resonance with molecular excitons; with other plasmonic nanostructures, particularly the Fano effect; and with nonplasmonic nanoparticles, such as the just-reported interaction with ferromagnetic nanoparticles. The theoretical as well as experimental challenges remaining to be elucidated are discussed.

One-step/one-pot decoration of oxide microparticles with silver nanoparticles.

Hypothesis: Heterogeneous nucleation of silver oxide (Ag2O) onto oxide microparticles (OMPs) followed by spontaneous thermal decomposition produce nanostructures made of OMPs decorated with silver nanoparticles (OMP|AgNPs).

Experiments: Colloidal chemistry methods have been used to produce the decoration of OMPs with silver nanoparticles (AgNPs), by carrying out the Ag2O precipitation/thermal decomposition. The process is driven in water enriched acetone medium containing NaOH, NH3, AgNO3 and SiO2MPs as substrate.

Combination flap surgery with resin-modified glass ionomer for the treatment of radicular lesions: a long-term follow-up.

This retrospective study evaluated the long-term clinical success of combination therapy using resin-modified glass ionomer (RMGI) with flap surgery in treating subgingival radicular defects. The study population consisted of 142 patients with 188 radicular defects. Clinical parameters (pocket depth, recession, clinical attachment level [CAL], and bleeding on probing) were evaluated.

Prophylactic probiotics to prevent death and nosocomial infection in preterm infants.

Background And Objective: It has been suggested that probiotics may decrease infant mortality and nosocomial infections because of their ability to suppress colonization and translocation of bacterial pathogens in the gastrointestinal tract. We designed a large double-blinded placebo-controlled trial using Lactobacillus reuteri to test this hypothesis in preterm infants.

Methods: Eligible infants were randomly assigned during the first 48 hours of life to either daily probiotic administration or placebo.

[Necrotizing enterocolitis among preterm newborns with early feeding].

Introduction: The development of necrotizing enterocolitis is a common and serious risk to newborns. It is caused by splanchnic bed vasoconstriction that can produce intestinal necrosis. The role of onset time, type and, speed enhancements of The factors of enteral feeding related with necrotizing enterocolitis genesis such as feeding onset, type and frequency are not well understood.

Rational design of plasmonic nanostructures for biomolecular detection: interplay between theory and experiments.

In this work, we report a simple strategy to obtain ultrasensitive SERS nanostructures by self-assembly and bioconjugation of Au nanospheres (NSs). Homodimer aggregates with an interparticle gap of around 8 nm are generated in aqueous dispersions by the highly specific molecular recognition of biotinylated Au NSs to streptavidin (STV), while random Au NS aggregates with a gap of 5 nm are formed in the absence of STV due to hydrogen bonding among biotinylated NSs. Both types of aggregates depict SERS analytical enhancement factors (AEF) of around 10(7) and the capability to detect biotin concentrations lower than 1 × 10(-12) M.

Retrieving the spatial distribution of cavity modes in dielectric resonators by near-field imaging and electrodynamics simulations.

For good performance of photonic devices whose working principle is based on the enhancement of electromagnetic fields obtained by confining light into dielectric resonators with dimensions in the nanometre length scale, a detailed knowledge of the optical mode structure becomes essential. However, this information is usually lacking and can only be indirectly obtained by conventional spectroscopic techniques. Here we unraveled the influence of wire size, incident wavelength, degree of polarization and the presence of a substrate on the optical near fields generated by cavity modes of individual hexagonal ZnO nanowires by combining scanning near-field optical microscopy (SNOM) with electrodynamics calculations within the discrete dipole approximation (DDA).