Adrenal insufficiency attributable to adrenal hemorrhage: long-term follow-up with reference to glucocorticoid and mineralocorticoid function and replacement.

Objective: To describe the long-term follow-up of acute adrenal insufficiency attributable to bilateral adrenal hemorrhage.

Methods: We performed a retrospective review of medical records of four patients who underwent follow-up for 6(1/2) to 19 years.

Results: Despite published reports of more than 500 patients with bilateral massive adrenal hemorrhage through 2001, no long-term data assessing the continuing requirements for glucocorticoid and mineralocorticoid replacement are available.