Synthesis and Characterization of a pH- and Temperature-Sensitive FeO-SiO-Poly(NVCL-co-MAA) Nanocomposite for Controlled Delivery of Doxorubicin Anticancer Drug.

This work reports the synthesis, characterization, and in vitro release studies of pH- and temperature-sensitive FeO-SiO-poly(NVCL-co-MAA) nanocomposite. FeO nanoparticles were prepared by chemical coprecipitation, coated with SiO by the Stöber method, and functionalized with vinyl groups. The copolymer poly(N-vinylcaprolactam-co-methacrylic acid) (poly(NVCL-co-MAA)) was grafted onto the functionalized FeO-SiO nanoparticles by free radical polymerization.

Inhibition of Phytopathogenic and Beneficial Fungi Applying Silver Nanoparticles In Vitro.

In the current research, our work measured the effect of silver nanoparticles (AgNP) synthesized from Larrea tridentata (Sessé and Moc. ex DC.) on the mycelial growth and morphological changes in mycelia from different phytopathogenic and beneficial fungi.

Biomimetic Growth of Hydroxyapatite on SiO Microspheres to Improve Its Biocompatibility and Gentamicin Loading Capacity.

The interest in multifunctional biomaterials to be implanted are also able to release drugs that reduce pain and inflammation or prevent a possible infection has increased. Bioactive materials such as silica (SiO) containing surface silanol groups contribute to the nucleation and growth of hydroxyapatite (HAp) in a physiological environment. Regarding biocompatibility, the spherical shape of particles is the desirable one, since it does not cause mechanical damage to the cell membrane.

Environmental friendly cold-mechanical/sonic enzymatic assisted extraction of genipin from genipap (Genipa americana).

An efficient cold-mechanical/sonic-assisted extraction technique was developed for extraction of genipin from genipap (Genipa americana) peel. Ultrasound assisted extraction (285 W, 24 kHz) was performed at 5, 10 and 15 °C for 5, 10 and 15 min. After cold-extraction, genipin was separated from pectin and proteins by aid of fungal pectinesterase.