Role of TLR1, TLR2 and TLR6 in the modulation of intestinal inflammation and elimination.

Background: Toll-like receptors (TLRs) are the major pattern recognition receptors that mediate sensing of a wide range of microorganisms. TLR2 forms heterodimers with either TLR1 or TLR6, broadening its ligand diversity against pathogens. TLR1, TLR2 and TLR6 have been implicated in the recognition of , an opportunistic fungal pathogen that colonizes the gastrointestinal tract.