Publications by authors named "Luigi Pusterla"
A Delphi consensus-seeking procedure was conducted to validate a list of ICD-9-CM codes that could help identify hospital admissions in which antimicrobials are more likely to be prescribed. The panel agreed to include 2967 codes out of 16229 (18.28%).
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- A multicenter observational study named CONDIVIDIAMO analyzed the effectiveness of monoclonal antibodies (mAbs) in reducing COVID-19 hospitalizations among outpatients with risk factors for severe disease.
- The study enrolled 1,534 participants and tracked outcomes over 28 days, recording hospitalizations and deaths, with results showing a 5.6% incidence of hospitalization or death after mAbs treatment.
- Key risk factors identified for increased hospitalization included older age and immunodeficiency, highlighting the importance of targeting vulnerable populations for mAb treatment.
What is the impact of SARS-CoV-2 pandemic on antimicrobial stewardship programs (ASPs)? The results of a survey among a regional network of infectious disease centres.
Antimicrob Resist Infect Control
August 2022
Article Synopsis
- The SARS-CoV-2 pandemic led to a noticeable decline in antimicrobial stewardship programs (ASPs) and an increase in antibiotic use, particularly in areas with high multidrug-resistant organisms (MDROs).
- A survey conducted in July 2021 revealed that 50% of the 18 infectious disease (ID) units experienced reduced ASP activity, with 38.9% completely suspending their programs during the pandemic.
- Hospitals that had established ASPs as a priority prior to the pandemic were more successful in reviving those programs after the initial COVID-19 waves, indicating that pre-existing commitment to ASPs was crucial for resilience during the crisis.
HIV and metabolic syndrome: a comparison with the general population.
J Acquir Immune Defic Syndr
August 2007
Objective: To compare the prevalence of metabolic syndrome (MS) in HIV-positive patients with that from a sample of a general Italian population.
Design: Cross-sectional study.
Methods: A total of 1263 HIV-infected patients 18 years of age or older were recruited in 18 centers for infectious diseases in northern and central Italy.
Purpose: This study set out to describe the frequency of lipodystrophy, and identify its risk factors, in HIV-positive patients treated with HAART containing at least one protease inhibitor (PI). We analyzed the data collected in the CISAI study.
Methods: The CISAI is a multicenter cohort study that has enrolled 1480 patients.