Colorectal cancer in the young: a possible role for immune surveillance?

Background: Younger patients with colorectal cancer (CRC) generally have better survival in spite of worse clinical and pathological features.

Methods: Twenty-six patients under 50 years operated for primary CRC were enrolled and matched 1:2:2 according to stage, tumor site and gender with 52 patients from 50 to 70 years and 52 patients over 70 years old.

Results: Patients under 50 years had a significantly longer overall, cancer specific and disease free survival (p = .

Synchronous polyps predict metachronous colorectal lesions after curative resection of colorectal cancer.

Background: The principal aim of endoscopic follow-up programs after curative resection of colorectal cancer (CRC) is to improve survival and identify local recurrence and metachronous CRC. The aim of our study was to identify the possible predictors of metachronous colorectal lesions.

Methods: The records of 348 consecutive patients with CRC and who completed at least 1 year of endoscopic follow-up after surgery were analyzed.

Management of ruptured hepatocellular carcinoma: implications for therapy.

Aim: To assess the treatment and tumor-related variables associated with outcome after treatment of spontaneously ruptured hepatocellular carcinoma (HCC).

Methods: Patients with ruptured HCC were identified. The complications, mortality and survival were assessed.