Familial mesothelioma of the pleura--a report of 40 cases.

A survey of 610 pleural mesotheliomas disclosed 40 familial cases. The diagnosis was histologically based in 39 cases, and confirmed by necropsy in 30. Occupational data were collected from the patients or from their relatives by personal interviews.

Schnabel cavernous degeneration: a vascular change of the aging eye.

Context: Schnabel cavernous degeneration is a histologic finding originally attributed to glaucoma; however, its cause and significance have been controversial.

Objective: To determine the basic cause of the formation of cavernous spaces in the proximal optic nerve and its clinical significance.

Methods: A retrospective analysis of 4500 autopsy eyes processed for histologic evaluation between 1967 and 1991.