Publications by authors named "Luigi Garufi"
Article Synopsis
- A study evaluated the effectiveness of a commercial sponge diffuser versus a custom-made cannula and no CO2 in preventing neurological events after aortic valve replacement surgery.
- Three patient groups were compared based on their CO2 delivery method, with a focus on outcomes like stroke, dizziness, and mechanical ventilation duration.
- Results showed that the sponge diffuser group had a significantly lower duration of mechanical ventilation, decreased 30-day mortality, and fewer neurological events compared to the other methods.
Article Synopsis
- Type A acute aortic dissection (TAAAD) is a serious medical emergency requiring immediate surgical intervention, and understanding treatment options is crucial for improving patient outcomes.
- A multicenter observational registry called AoArch has been established, combining data from four cardiac surgery centers in Europe to analyze the effects of hemiarch repair (HAR) versus extended arch repair (EAR) on patient outcomes following TAAAD surgery.
- The study will assess various factors, such as patient co-morbidities and surgical strategies, to measure both early and late adverse events, with a focus on defining mortality rates and complications related to TAAAD treatments.
Article Synopsis
- The study evaluates the long-term outcomes of two types of rings used in valve-sparing root replacement surgery: a calibrated expansible extra-aortic ring and a homemade Dacron ring.
- Among 486 patients, those with the extra-aortic ring showed significantly better long-term survival, lower rates of reoperation, and reduced recurrence of severe aortic insufficiency compared to the Dacron ring.
- The extra-aortic ring also demonstrated superior performance in preventing annular dilation and preserving root expansibility over time.
Redo aortic surgery poses significant challenges, particularly in complex scenarios involving congenital heart conditions that have been previously operated on several years prior. The integration of three-dimensional (3D) reconstruction and printing holds immense potential to greatly improve surgical precision, particularly in critical situations.
View Article and Find Full Text PDFAlthough mid- and long-term outcomes after the Ross procedure for aortic valve disease have been increasingly improving over the years, this is still a rather challenging operation in neonates and small children. This is particularly true for patients with associated congenital heart defects and critical clinical conditions. Herein we describe the application of this procedure as a rescue operation in emergency circumstances in a low-birth-weight neonate with severe aortic stenosis, aortic regurgitation and mitral regurgitation after a previous aortic coartectomy.
View Article and Find Full Text PDFBackground: Transplantation in the management of end-stage organ failure in patients with Anderson- Fabry disease is still a matter of debate due to a lack of data regarding long-term outcomes and prognosis.
Observations: Most of the cases in the literature did not receive enzyme-replacement therapy (ERT), or received it only years after transplantation. Based on our experience, we describe here the long-term results of heart transplant in combination with early ERT.
Objectives: The goal of this multicentre retrospective study was to compare long-term clinical and haemodynamic outcomes of the Carpentier-Edwards Magna Ease (CEME) bioprosthesis by patient age.
Methods: We included consecutive patients who underwent isolated and combined surgical aortic valve replacement (AVR) with CEME valve between January 2008 and March 2020 at 4 cardiac surgery centres in Italy. Survival distribution was evaluated at follow-up according to age and surgery type (combined or isolated AVR), together with freedom from structural valve deterioration (SVD), reoperation and combined events, i.
Aortic annuloplasty has demonstrated to be a protective factor in valve-sparing root replacement and aortic valve repair. Both reimplantation for aortic root aneurysms and external ring annuloplasty for isolated aortic regurgitation have demonstrated good long-term results. The aim of this anatomical study is to compare aortic reimplantation with Valsalva graft with aortic external ring annuloplasty in bicuspid aortic valves, analyzing their morphological features with CT scan.
View Article and Find Full Text PDFAortic root anatomy after aortic valve reimplantation.
J Thorac Cardiovasc Surg
April 2023
Objective: During the last decade, special concerns have been raised about the anatomic relationships among the sinotubular junction, ventricular-aortic junction, and virtual basal ring to improve the results of root reconstruction. The aim of this study is to evaluate the in vivo anatomy of the aortic root after reimplantation with the Valsalva graft and the anatomic relationship between its components.
Methods: We analyzed 10 consecutive patients with tricuspid aortic valves who underwent reimplantation with the Valsalva graft between September and December 2019.
Introduction: Progressive saphenous vein graft (SVG) failure remains a key limitation to the long-term success of coronary artery bypass grafting (CABG). SVG disease after the first year is dominated by intimal hyperplasia, which predisposes the SVG to thrombosis and accelerated atherosclerosis. The objective of this study was to review and summarize the latest experimental and clinical data on the use of mechanical external stents for vein grafts.
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