Publications by authors named "Luigi DI Marino"
Background: Hormone receptor-positive tumors are unlikely to exhibit a complete pathological tumor response. The association of CDK 4/6 inhibitor plus hormone therapy has changed this perspective.
Case Presentation: In this study, we retrospectively reviewed the charts of patients with a diagnosis of luminal A/B advanced/metastatic tumors treated with a CDK 4/6 inhibitor-based therapy.
Article Synopsis
- SARS-CoV-2 vaccination is highly recommended for fragile patients, particularly those undergoing cancer treatments, and post-marketing surveillance is necessary for this group.
- The study analyzed data from 136 cancer patients who received mRNA vaccines (Pfizer-BioNTech and Moderna) and found significant occurrences of leukopenia after vaccination, especially in those receiving chemotherapy and chemo-immunotherapy.
- While a small portion of patients experienced treatment delays, the vaccine did not significantly disrupt treatment schedules, indicating the need for more extensive studies to better understand the vaccine's effects in this vulnerable population.
The incidence of multifocal (MF) and multicentric (MC) breast cancer has a wide variation among different clinical studies, mostly due to the lack of a standardized classification and definition of these two separate entities. The optimal surgical treatment for multiple ipsilateral breast cancer remains a long debated subject. Multifocal and multicentric breast cancer is usually considered a relative contraindication for breast conserving therapy (BCT).
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