Publications by authors named "Luigi D Biase"

Article Synopsis
  • Wolff-Parkinson-White (WPW) syndrome is a condition marked by specific ECG changes leading to premature heart contractions and recurrent rapid heart rhythms.
  • The most frequent arrhythmia linked to WPW is atrioventricular re-entry tachycardia (AVRT), while atrial fibrillation (AF) can occur in about half of WPW patients, raising concerns for potential misdiagnosis and incorrect treatments.
  • This review emphasizes the importance of recognizing ECG signs of pre-excited AF and discusses effective management strategies, including both medication and invasive procedures, to enhance patient care.
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Transcatheter radiofrequency ablation has been widely introduced for the treatment of tachyarrhythmias. The demand for catheter ablation continues to grow rapidly as the level of recommendation for catheter ablation. Traditional catheter ablation is performed under the guidance of X-rays.

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Article Synopsis
  • The article has been retracted at the request of the authors due to incorrect specifications in the methods section related to ablation settings.
  • These settings could potentially connect to a specific pulsed field ablation technology currently under FDA investigation.
  • The authors apologize for the oversight and any inconvenience caused, and there may be a reference to previous plagiarized work if applicable.
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Background: Transvenous lead extraction (TLE) is standard of care for the management of patients with cardiac implantable electronic device infection or lead-related complications. Currently, objective data on TLE in Latin America is lacking.

Objective: To describe the current practice standards in Latin American centers performing TLE.

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Objective: To assess the safety and efficacy of a novel immunosuppressive regimen-combination Methotrexate/Prednisone (cMtx/P)-in the management of severe refractory rPPP.

Methods: In this multicenter, nonrandomized, retrospective, observational study, 408 consecutive patients diagnosed with persistent rPPP between 2017 and 19 were included. Patients with refractory symptoms despite 3 months of conventional therapy were initiated on a 4-week regimen of oral steroids.

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Article Synopsis
  • Cardiac arrest occurs in about 1 in 50,000 athletes, primarily due to life-threatening ventricular arrhythmias (VAs) linked to inherited or acquired cardiac diseases.
  • Athletes exhibit unique heart remodeling and specific patterns of VAs, but there is limited data on the long-term effects of VAs in this group, making treatment decisions complex.
  • This review discusses the prevalence, ECG characteristics, causes, and potential outcomes of VAs in athletes, emphasizing the need for further understanding of their eligibility for sports post-catheter ablation.
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Catheter ablation (CA) is an effective treatment for ventricular arrhythmias (VA), with a potential for complications. The presence of structural heart disease (SHD) is associated with a higher complication rate although there is no data comparing CA of VA between patients with SHD and those without. We aimed to compare trends, morbidity, and mortality associated with real world practice of CA for VA (ventricular tachycardia and premature ventricular contraction) based on the presence of SHD.

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Atrial fibrillation remains the most common arrhythmia worldwide, with pulmonary vein isolation (PVI) being an essential component in the treatment of this arrhythmia. In view of the close proximity of the oesophagus with the posterior wall of the left atrium, oesophageal injury prevention has become a major concern during PVI procedures. Oesophageal changes varying from erythema to fistulas have been reported, with atrio-oesophageal fistulas being the most feared as they are associated with major morbidity and mortality.

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We aimed to perform a meta-analysis from eligible studies to analyze the true impact of QL when compared with BL with regard to post-procedural outcomes including lead deactivation, revision or replacement. Many observational and retrospective studies showed that quadripolar left ventricular leads (QL) are associated with better outcomes and fewer complications when compared with bipolar leads (BL). We performed a comprehensive literature search through June 30, 2015 using: quadripolar, bipolar, left ventricular lead and CRT in Pubmed, Ebsco and google scholar databases.

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Article Synopsis
  • Silent brain lesions can occur during atrial fibrillation (AF) catheter ablation due to the procedure's thrombogenicity, with recent studies suggesting uninterrupted anticoagulation can reduce the risk of silent cerebral ischemia (SCI) to 2%.
  • Asymptomatic cerebral lesions discovered during ablation may indicate a higher risk of long-term neuropsychological issues, such as dementia, but current research lacks definitive links between these events and cognitive decline.
  • While larger cerebral lesions are associated with cognitive issues, they are rare immediately after AF ablation; most lesions are small or medium-sized and often improve over time, suggesting that effective AF treatment could lower larger SCI risks.
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Background: Pneumothorax (PTX) is a major cause of morbidity associated with cardiac implantable electronic devices (CIEDs). We sought to evaluate predictors of PTX at our centers during CIED implantations, including the venous access technique utilized, as well as to determine morbidity and costs associated with PTX.

Methods: We reviewed records of all patients undergoing cardiac device implant or revision with new venous access at our institutions between 2008 and 2014.

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Background: Early repolarization (ER), once thought to be a benign finding on electrocardiograph (ECG), has recently been associated with an increased risk of sudden cardiac death. As there are limited data in the Hispanic population, we investigated possible associations between automated ECG ER readings and overall mortality, using the classic definition involving J-point elevation with ST segment elevation.

Methods: An ECG and electronic medical record (EMR) database from a regional medical center was interrogated.

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Ventricular arrhythmias (VAs) arising from the right ventricular outflow tract (RVOT) are a common and heterogeneous entity. Idiopathic right ventricular arrhythmias (IdioVAs) are generally benign, with excellent ablation outcomes and long-term arrhythmia-free survival, and must be distinguished from other conditions associated with VAs arising from the right ventricle: the differential diagnosis with arrhythmogenic right ventricular cardiomyopathy/dysplasia (ARVC/D) is therefore crucial because VAs are one of the most important causes of sudden cardiac death (SCD) in young individuals even with early stage of the disease. Radiofrequency catheter ablation (RFCA) is a current option for the treatment of VAs but important differences must be considered in terms of indication, purposes and procedural strategies in the treatment of the two conditions.

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The cornerstone of the new imaging technologies to treat complex arrhythmias is the electroanatomic (EAM) mapping. It is based on tissue characterization and in particular on determination of low potential region and dense scar definition. Recently, the identification of fractionated isolated late potentials increased the specificity of the information derived from EAM.

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