Publications by authors named "Luigi Capodicasa"

Background & Aims: Noninvasive tests (NITs) for ruling-out clinical significant portal hypertension (CSPH) and high-risk varices (HRVs) in patients with primary biliary cholangitis (PBC) and compensated advanced chronic liver disease (cACLD) are lacking. We evaluated NITs in these patients and the influence of cholestasis on their performance.

Methods: Consecutive patients from the "Italian PBC registry" and 2 United Kingdom large-volume PBC referral centers with upper endoscopy within 6 months from biochemical evaluation and transient elastography were included.

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Article Synopsis
  • - The study investigates the significance of antinuclear antibodies (ANA) patterns in patients with liver diseases, focusing on autoimmune liver disease (AILD).
  • - Out of 396 patients tested, 33% were diagnosed with AILD, predominantly autoimmune hepatitis (AIH); specific ANA patterns showed varied prevalence among different liver diseases.
  • - The results indicate that certain ANA patterns (like AC1 for AIH and AC21 for primary biliary cholangitis) correlate strongly with specific liver conditions, suggesting their potential importance in clinical diagnosis.
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Objectives: To investigate how the changes of left ventricle ejection fraction (LVEF) between admission and discharge affected the long-term outcome in patients who underwent percutaneous edge-to-edge mitral valve repair for secondary mitral regurgitation.

Background: An acute impairment of LVEF after surgical repair of mitral regurgitation, known as afterload mismatch, has been associated with increased all-cause mortality. Afterload mismatch after percutaneous edge-to-edge mitral valve repair has been postulated to be a transient phenomenon.

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