Publications by authors named "Luehr J"
The intestinal immune system must concomitantly tolerate food and commensals and protect against pathogens. Antigen-presenting cells (APCs) orchestrate these immune responses by presenting luminal antigens to CD4 T cells and inducing their differentiation into regulatory (pTreg) or inflammatory (Th) subsets. We used a proximity labeling method (LIPSTIC) to identify APCs that presented dietary antigens under tolerizing and inflammatory conditions and understand cellular mechanisms by which tolerance to food is induced and can be disrupted by infection.
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- Face masks are effective in reducing SARS-CoV-2 transmission, but people often avoid wearing them due to discomfort.
- A study identified key factors affecting mask comfort: air resistance, water vapor permeability, and face temperature change, using surveys and physiological experiments.
- Machine learning models, particularly a multiple linear regression model, were developed to predict mask comfort scores, aiming to enhance user experience and encourage higher compliance with mask-wearing during the pandemic.
In order to evaluate the equivalence of interviewer-administered and computer-administered forms of the substance use disorder diagnostic schedule (SUDDS), both forms were presented to 100 substance-dependent inpatients. An additional 101 psychiatric outpatients were administered one form or the other. For patients who received both forms of the SUDDS, the percentage agreement ranged from 96% for the classification of a lifetime diagnosis of alcohol abuse/dependence to 88% for the classification of current diagnosis of alcohol abuse/dependence (kappa coefficients ranged from 0.
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