In Vivo tissue healing mechanism at the intestinal anastomosis site following high-frequency electric welding.

To investigate the effect of High-Frequency Electric Welding (HFEW) on intestinal tissue healing, we performed end-to-end anastomosis experiments in New Zealand rabbits. Within one week post-surgery, animals exhibited normal vital signs, replaced necrotic tissue with healthy collagen, and showed improved tissue strength while inflammation decreased. By day 60, tissue pathology and function fully recovered, resembling normal tissue.

Global burden of cardiovascular disease mortality attributable to secondhand smoke, 1990-2019: Systematic analysis of the Global Burden of Disease Study 2019.

Background: Few studies have globally assessed the cardiovascular disease (CVD) mortality burden attributable to secondhand smoke. We aimed to address this research gap.

Methods: We used a systematic analysis design using data from the Global Burden of Disease Study 2019.

Evaluating the safety and effectiveness of α-blockers versus mirabegron for medical expulsive therapy in ureteral calculi: A Systematic review and meta-analysis.

Introduction And Aim: The main categories of drugs employed for medical expulsive therapy in patients with ureteral calculi (UC) are alpha-blockers (α-B) and beta-adrenoceptor agonists. This meta-analysis evaluated the safety and effectiveness of α-B versus mirabegron (MIR) in treating UC.

Methods: From January 1980 to October 2024, we extensively searched the Pubmed, Web of science, Cochrane and EMBASE databases to identify randomized controlled trials (RCTs) that compared the effectiveness of α-B and MIR in managing UC.

Prevalence and risk factors of sarcopenia in patients with stroke: a systematic review and meta-analysis.

Stroke is the second leading cause of death and the third-leading cause of disability in the world. The skeletal muscles play a key role in disability following stroke. Although many studies have reported the prevalence and risk factors of sarcopenia in patients with stroke, the results have not been synthesized.

An Efficient and Flexible Bifunctional Dual-Band Electrochromic Device Integrating with Energy Storage.

Dual-band electrochromic devices capable of the spectral-selective modulation of visible (VIS) light and near-infrared (NIR) can notably reduce the energy consumption of buildings and improve the occupants' visual and thermal comfort. However, the low optical modulation and poor durability of these devices severely limit its practical applications. Herein, we demonstrate an efficient and flexible bifunctional dual-band electrochromic device which not only shows excellent spectral-selective electrochromic performance with a high optical modulation and a long cycle life, but also displays a high capacitance and a high energy recycling efficiency of 51.

Sodium-glucose cotransporter 2 inhibitors and contrast-induced nephropathy risk: a meta-analysis.

Background: Contrast-induced nephropathy (CIN) is an adverse renal event that occurs following the administration of contrast media for diagnostic procedures or therapeutic angiographic intervention. Nevertheless, there is currently no efficacious and safe agents for the treatment of CIN, except for hydration. We aimed to conduct a meta-analysis to verify the potential nephroprotective role of sodium-glucose cotransporter 2 inhibitors (SGLT2is) in the prevention of CIN.

Neural Modulation Alteration to Positive and Negative Emotions in Depressed Patients: Insights from fMRI Using Positive/Negative Emotion Atlas.

Background: Although it has been noticed that depressed patients show differences in processing emotions, the precise neural modulation mechanisms of positive and negative emotions remain elusive. FMRI is a cutting-edge medical imaging technology renowned for its high spatial resolution and dynamic temporal information, making it particularly suitable for the neural dynamics of depression research.

Methods: To address this gap, our study firstly leveraged fMRI to delineate activated regions associated with positive and negative emotions in healthy individuals, resulting in the creation of the positive emotion atlas (PEA) and the negative emotion atlas (NEA).

Functional Characterization and Toxicological Study of in Weaned Pigs.

(CM), a well-known parasitic fungus that grows on the larvae of , has a variety of pharmacological activities. However, little is known about its safe dosage for animals, including pigs. To explore its effect on intestinal health and evaluate its safe dosage, 30 weaned pigs were randomly allotted to five groups and fed with a basal diet supplemented with different doses of CM for 42 days.

Microstructures of Directionally Solidified NbTiFe Alloy and Its Hydrogen Permeation Properties in the Presence of HS.

Currently, the main limitations of Pd-coated Nb-TiFe dual-phase alloys include insufficient hydrogen permeability, susceptibility to hydrogen embrittlement (HE), and poor tolerance of HS poisoning. To address these issues, this study proposes a series of improvements. First, a novel NbTiFe alloy composed of a well-aligned Nb-TiFe eutectic was successfully prepared using directional solidification (DS) technology.

Controllable Synthesis of Three-Dimensional Chiral Au Nanoflowers Induced by Cysteine with Excellent Biocompatible Properties.

Chiral molecules are ubiquitous in nature and biological systems, where the unique optical and physical properties of chiral nanoparticles are closely linked to their shapes. Synthesizing chiral plasmonic nanomaterials with precise structures and tunable sizes is essential for exploring their applications. This study presents a method for growing three-dimensional chiral gold nanoflowers (Au NFs) derived from trisoctahedral (TOH) nanocrystals using D-cysteine and L-cysteine as chiral inducers.

The Preparation of High-Performance MoO Nanorods for 2.1 V Aqueous Asymmetric Supercapacitor.

In order to broaden the working voltage (1.23 V) of aqueous supercapacitors, a high-performance asymmetric supercapacitor with a working voltage window reaching up to 2.1 V is assembled using a nanorod-shaped molybdenum trioxide (MoO) negative electrode and an activated carbon (AC) positive electrode, as well as a sodium sulfate-ethylene glycol ((NaSO-EG) electrolyte.

Dual-Valence Copper Nanostructures with Cu/Cu Interfaces for High-Sensitivity Glucose Electrochemical Sensing.

Copper-based materials, renowned for their redox versatility and conductivity, have extensive applications in electrochemical sensing. Herein, we construct stable Cu/Cu interfaces within dual-valence copper nanostructures to achieve enhanced sensitivity in glucose sensing. By employing a hydrolysis method to tune Cu/Cu ratios precisely, we achieved an optimal electrochemical interface with heightened stability and reactivity.

Carbonized Plant Powder Gel for Rapid Hemostasis and Sterilization in Regard to Irregular Wounds.

Irregularly shaped wounds cause severe chronic infections, which have attracted worldwide attention due to their high prevalence and poor treatment outcomes. In this study, we designed a new composite functional dressing consisting of traditional Chinese herb carbonized plant powder (CPP) and a polyacrylic acid (PAA)/polyethylenimine (PEI) gel. The rapid gelation of the dressing within 6-8 s allowed the gel to be firmly attached to an irregularly shaped wound surface and avoided powder detachment.

Rice-Fish Farming Improved Antioxidant Defences, Glucose Metabolism, and Muscle Nutrient of in Sichuan Province.

Rice-fish farming is an ancient and enduring aquaculture model in China. This study aimed to assess the variations in digestive enzymes, antioxidant properties, glucose metabolism, and nutritional content between reared in paddy fields and ponds. Notably, the levels of amylase and trypsin in from rice paddies were considerably higher compared to those from ponds.

Transcriptomic and Metabolomic Analysis Reveals Multifaceted Impact of Gcn5 Knockdown in Development.

General control nonderepressible 5 (Gcn5) is a lysine acetyltransferase (KAT) that is evolutionarily conserved across eukaryotes, with two homologs (Kat2a and Kat2b) identified in humans and one (Gcn5) in . Gcn5 contains a P300/CBP-associated factor (PCAF) domain, a Gcn5-N-acetyltransferase (GNAT) domain, and a Bromodomain, allowing it to regulate gene expression through the acetylation of both histone and non-histone proteins. In , Gcn5 is crucial for embryonic development, with maternal Gcn5 supporting early development.

Diversity of Species Associated with Trunk Diseases of (Peach) in Northern China.

Peach () is widely cultivated in China, but fungal diseases, particularly Cytospora canker, significantly impact tree health, reducing fruit yield and economic value. This disease mainly weakens tree branches and trunks, sometimes leading to tree death. There are no updated studies on the diversity of species associated with peach Cytospora canker in northern China.

Exogenous Trehalose Assists in Resisting High-Temperature Stress Mainly by Activating Genes Rather than Entering Metabolism.

is a typical aroma-producing yeast in food brewing, but it has low heat resistance and poor proliferation ability at high temperature. Trehalose is generally considered to be a protective agent that helps stable yeast cells resist heat shock stress, but its functional mechanism for yeast cells in the adaptation period under heat stress is unclear. In this study, the physiological metabolism changes, specific gene transcription expression characteristics, and transcriptome differences of under different carbon sources under high-temperature stress (40 °C) were compared to explore the mechanism of trehalose inducing to recover and proliferate under high-temperature stress during the adaptation period.

Comprehensive Genomic and Proteomic Analysis Identifies Effectors of f. sp. .

wilt in eggplant caused by f. sp. is a major devastating soil-borne disease on a worldwide scale.

Oxygenase Ppo-Regulated Moldy Volatiles Affect Growth, Pathogenicity and Patulin Biosynthesis of Through G Protein Signaling.

Precocious sexual inducer (psi)-producing oxygenases (Ppos) participate in the production of C8 moldy volatile compounds (MVOCs), and these compounds could act as signal molecules modulating G protein signaling cascades, which participates in the growth and development, secondary metabolisms and pathogenicity of filamentous fungi. In this study, PePpoA and PePpoC proteins were identified in . The deletion of decreased C8 MVOC production in , while they were not detected in the strain ( < 0.

Pectiniferosides A-J: Diversified Glycosides of Polyhydroxy Steroids Isolated from the Sea Star .

To optimize the utilization of the sea star , which has demonstrated potential pharmaceutical properties in Chinese folk medicine, ten glycosides of polyhydroxy steroids, pectiniferosides A-J (-), were isolated and characterized. These compounds possess 3β, 6α, 8, 15α (or β), 16β-pentahydroxycholestane aglycones with sulfated and (or) methylated monosaccharides. The chemical structures of - were determined using NMR spectroscopy and HR-ESI-MS.

Identification and Validation of qRT-PCR Reference Genes for Analyzing Responses to High-Temperature Stress.

Quantitative real-time PCR (qRT-PCR) is an essential tool for analyzing and selecting stable reference genes. In order to screen for suitable reference genes under high-temperature stress conditions in , this study measured the relative expression levels of 17 candidate reference genes using qRT-PCR. Among these, four are traditional reference genes, while the remaining thirteen are candidate reference genes with no previous reports on their use as reference genes.

Exploring Imaging Applications of a Red-Emitting π-Acceptor (π-A) Pyrene-Benzothiazolium Dye.

Bright biocompatible fluorescent imaging dyes with red to near-infrared (NIR) emissions are ideal candidates for fluorescence microscopy applications. Pyrene-benzothiazolium hemicyanine dyes are a new class of lysosome-specific probes reported on recently. In this work, we conduct a detailed implementation study for a pyrene-benzothiazolium derivative, BTP, to explore its potential imaging applications in fluorescence microscopy.

Development of a Novel Colorimetric pH Biosensor Based on A-Motif Structures for Rapid Food Freshness Monitoring and Spoilage Detection.

Accurate methods for assessing food freshness through colorimetric pH response play a critical role in determining food spoilage and ensuring food quality standards. This study introduces a novel unlabeled DNA sequence, poly-dA, designed to exploit the colorimetric properties of both the single strand and the fold-back A-motif structure in conjunction with gold nanoparticles (AuNPs) under varying pH conditions. When exposed to storage temperatures of 4 °C and 25 °C, the color variations in the AuNP solution, influenced by pH level changes in mutton and sea bass samples' different storage periods, are easily discernible to the naked eye within a minute.

Research on Multimodal Control Method for Prosthetic Hands Based on Visuo-Tactile and Arm Motion Measurement.

The realization of hand function reengineering using a manipulator is a research hotspot in the field of robotics. In this paper, we propose a multimodal perception and control method for a robotic hand to assist the disabled. The movement of the human hand can be divided into two parts: the coordination of the posture of the fingers, and the coordination of the timing of grasping and releasing objects.