Insulin Pump Therapy - Influence on Body Fat Redistribution, Skeletal Muscle Mass and Ghrelin, Leptin Changes in T1D Patients.

Background: To report changes in body composition and biochemical parameters in patients with type 1 diabetes mellitus (T1D) after switching from multiple daily injection (MDI) to continuous subcutaneous insulin infusion (CSII).

Methods: 31 patients switched over from MDI to CSII. Body composition, biochemical parameters, glycaemic variability (GV) and level of physical activity were evaluated before and 6 months on CSII.

Prevalence of diabetes mellitus and metabolic syndrome in Slovakia.

Background: Slovakia is a country with high prevalence of diabetes mellitus (DM) and coronary heart disease (CHD), but the reason of west-east gradient prevalence in Europe is not clear.

Methods: We analyzed 1517 subjects responding to structure of Slovak adult population according to age, sex and regions. Self-reporting CHD risk factors, waist circumference, body mass index (BMI), blood pressure, levels of fasting and 2h glucose, triglycerides, and HDL cholesterol were examined.