OP-1 Compared with Iliac Crest Autograft in Instrumented Posterolateral Fusion: A Randomized, Multicenter Non-Inferiority Trial.

Background: Spinal fusion with the use of autograft is a commonly performed procedure. However, harvesting of bone from the iliac crest is associated with complications. Bone morphogenetic proteins (BMPs) are extensively used as alternatives, often without sufficient evidence of safety and efficacy.

Influence of transforaminal lumbar interbody fusion procedures on spinal and pelvic parameters of sagittal balance.

Introduction: Restitution of sagittal balance is important after lumbar fusion, because it improves fusion rate and may reduce the rate of adjacent segment disease. The purpose of the present study was to describe the impact of transforaminal lumbar interbody fusion (TLIF) procedures on pelvic and spinal parameters and sagittal balance.

Materials And Methods: Forty-five patients who had single-level TLIF were included in this study.

Oncogenous osteomalacia and myopericytoma of the thoracic spine: a case report.

Study Design: A case report.

Objective: To illustrate a rare case of oncogenous osteomalacia caused by a spinal thoracic myopericytoma.

Summary Of Background Data: Osteomalacia related to a tumor is well known.

Acute spontaneous spinal epidural hematoma: an important differential diagnosis in patients under clopidogrel therapy.

Background Context: Spontaneous spinal epidural hematoma (SSEH) is an infrequent spinal pathology. Although it is related to numerous risk factors, its etiology remains unclear.

Purpose: The aim of this article was to review the most important data in the literature about SSEH and to propose clopidogrel (Plavix) therapy as a risk factor.

Is there a sagittal imbalance of the spine in isthmic spondylolisthesis? A correlation study.

Recent studies suggested a predominant role of spinopelvic parameters to explain lumbosacral spondylolisthesis pathogeny. We compare the pelvic incidence and other parameters of sagittal spinopelvic balance in adolescents and young adults with developmental spondylolisthesis to those parameters in a control group of healthy volunteers. We compared the angular parameters of the sagittal balance of the spine in a cohort of 244 patients with a developmental L5-S1 spondylolisthesis with those of a control cohort of 300 healthy volunteers.

Traumatic dislocation of the lumbosacral junction diagnosis, anatomical classification and surgical strategy.

Traumatic lumbosacral dislocation is a rare lesion often characterised by a fracture dislocation of L5-S1 articular facets associated with anterior L5 slipping. Because of its rarity, the surgical strategy of lumbosacral traumatic dislocation remains controversial. We report the most important series of traumatic lumbosacral dislocation.

Neurological and functional outcome after unstable cervicothoracic junction injury treated by posterior reduction and synthesis.

Background Context: Unstable lesions of the cervicothoracic junction present a severe clinical problem for diagnosis, treatment, and prognosis.

Purpose: The objective of the present study was to evaluate the neurological and functional outcomes following surgical treatments which combine in all cases posterior reduction and stabilization.

Study Design: Retrospective clinical and radiological study.

Spinal tuberculosis: a longitudinal study with clinical, laboratory, and imaging outcomes.

Objectives: To study imaging changes associated with spinal tuberculosis (ST) over time and evaluate their association with clinical and laboratory data.

Methods: Between 1997 and 2004, patients with proven ST in our institution were prospectively enrolled and treated for 1 year. Clinical and laboratory data were collected at baseline and every 3 months.

[Adult spinal deformities].

Contrary to a commonly held notion, scoliosis, and especially lumbar and thoracolumbar scoliosis, can develop during adulthood. Its evolution is slow and insidious and involves both the anatomic aspect of the curve and the functional aspect (development or worsening of painful spinal or radicular symptoms and/or disequilibrium). This finding underlines the necessity of a regular and extended monitoring of all patients presenting with such a condition.

Chondroblastoma of the lumbar spine. Report of two cases and review of the literature.

Chondroblastoma is a benign cartilaginous neoplasm that generally affects the appendicular skeleton. Twenty-six cases of spinal chondroblastoma have been reported in the past 50 years, only six of which were located in the lumbar region. The authors report two cases involving this exceptional location.

Comparative study of postoperative and spontaneous pyogenic spondylodiscitis.

Objectives: Postoperative spondylodiscitis (POS) is poorly characterized, partly owing to its rarity. The aim of this prospective study was to compare the clinical, biological, bacteriological, and imaging features of postoperative and spontaneous spondylodiscitis (SS).

Methods: A multidisciplinary spondylodiscitis cohort follow-up study was conducted between February 1999 and June 2003 in a 500-bed teaching hospital.

Radiographic analysis of the sagittal alignment and balance of the spine in asymptomatic subjects.

Background: There is an increasing recognition of the clinical importance of the sagittal plane alignment of the spine. A prospective study of several radiographic parameters of the sagittal profile of the spine was conducted to determine the physiological values of these parameters, to calculate the variations of these parameters according to epidemiological and morphological data, and to study the relationships among all of these parameters.

Methods: Sagittal radiographs of the head, spine, and pelvis of 300 asymptomatic volunteers, made with the subject standing, were evaluated.