Tenosynovial Giant Cell Tumor (TGCT) is a group of typically benign lesions arising from the synovium of joints, bursae and tendon sheaths. Depending on their growth pattern and clinical course, they are divided into localized and diffuse types. It is predominantly caused by a mutation in the stromal cells of the synovial membrane leading to overexpression of the colony stimulating factor 1 that recruits CSF1R-expressing cells of the mononuclear phagocyte lineage into the tumor mass.
View Article and Find Full Text PDFIntroduction: The intraneural ganglion cyst of the tibial nerve is very rare, especially at the level of an ankle and a foot. There are 15 previous reports of the tibial intraneural ganglion cyst within the tarsal tunnel or the popliteal fossa. The authors present an infrequent case of the tibial intraneural ganglion at the level of the tarsal tunnel diagnosed by an ultrasound examination and provide a review of the case studies described earlier in the available literature.
View Article and Find Full Text PDFOne of significant challenges faced by diabetologists, surgeons and orthopedists who care for patients with diabetic foot syndrome is early diagnosis and differentiation of bone structure abnormalities typical of these patients, i.e. osteitis and Charcot arthropathy.
View Article and Find Full Text PDFCarpal tunnel syndrome is the most frequent neuropathy of the upper extremity, that mainly occurs in manual workers and individuals, whose wrist is overloaded by performing repetitive precise tasks. In the past it was common among of typists, seamstresses and mechanics, but nowadays it is often caused by long hours of computer keyboard use. The patient usually complains of pain, hypersensitivity and paresthesia of his hand and fingers in the median nerve distribution.
View Article and Find Full Text PDFThe paper presents a case of Charcot foot in a patient with long standing type 2 diabetes and complicated by peripheral neuropathy. It was initially diagnosed by an ultrasound examination and subsequently confirmed by an X-ray and an magnetic resonance imaging. Diabetic neuropathy is nowadays the most frequent cause of Charcot arthropathy, although it can be also a result of other diseases of the nervous system.
View Article and Find Full Text PDF