Publications by authors named "Ludmila de Oliveira Muniz Koch"
Purpose: Choroid plexus tumors (CPT) are rare entities, and even rarer in adulthood.
Methods: A retrospective consecutive series of 24 adult CPT patients was reviewed.
Results: We described 24 adult CPTs.
Article Synopsis
- A phase 3 trial found that neoadjuvant treatment with nivolumab plus chemotherapy improved event-free survival in patients with resectable non-small-cell lung cancer (NSCLC) compared to chemotherapy alone, with 70.2% of the nivolumab group remaining event-free at 18 months, versus 50.0% in the chemotherapy group.!* -
- Patients receiving nivolumab also had a significantly higher rate of pathological complete response (25.3%) compared to those on chemotherapy (4.7%), indicating better treatment efficacy.!* -
- The safety profile was similar between both groups, with 32.5% of nivolumab patients experiencing grade 3 or 4 treatment-related adverse events
Article Synopsis
- Population aging presents significant challenges for cancer care, especially in low- and middle-income countries (LMIC), including the diverse Latin American region.
- This review highlights recent progress in Mexico, Brazil, and Chile regarding educational, research, and clinical efforts in geriatric oncology.
- The initiatives aim to reshape healthcare professionals' attitudes towards older adult care and enhance treatment approaches for elderly cancer patients.
Background: The incidence of most hematologic malignancies increases with age. Hematopoietic stem cell transplantation (HSCT) provides a potentially life-prolonging or curative option for many patients in this scenario. Limited data assessed from computed tomography (CT) images are available on muscle mass and density outcomes after HSCT.
View Article and Find Full Text PDFObjectives: To evaluate the results of the comprehensive geriatric assessment (CGA) before allogeneic hematopoietic stem cell (HSCT) transplantation in patients aged 60 years and over.
Methods: We evaluated all consecutive patients undergoing CGA before HSCT between September 2011 and July 2018 in a private hospital in Brazil. We also evaluated the Hematopoietic Cell Transplantation-Specific Comorbidity Index (HCT-SCI) and the Disease Risk Index (DRI).
The Brazilian Nutritional Consensus in Hematopoietic Stem Cell Transplantation: Elderly was elaborated by nutritionists, nutrologists and hematologists physicians from 15 Brazilians reference centers in hematopoietic stem cell transplantation, in order to emphasize the importancy of nutritional status and the body composition during the treatment, as well as the main characteristics related to patient's nutritional assessment. Establishing the consensus, we intended to improve and standardize the nutritional therapy during the hematopoietic stem cell transplantation. The Consensus was approved by the Brazilian Society of Bone Marrow Transplantation.
View Article and Find Full Text PDF