Transcranial Doppler in hemoglobin SC disease.

Background: Stroke is a severe clinical disorder in sickle cell disease (SCD), and few studies have evaluated transcranial Doppler (TCD) flow velocities in hemoglobin SC disease (HbSC). The guidelines for stroke risk are based on evaluations in sickle cell anemia (SCA) or HbS/β thalassemia.

Procedure: In this study, we compare cerebral blood flow in patients with SCD stratified by genotypes.