Long-term evaluation of the effect of middle ear effusion on the vestibular system in children.

Background: Otitis media with effusion (OME) is one of the most common clinical conditions in childhood. Fluid accumulation in the middle ear may impact inner ear.

Objectives: The purpose of this random sample cohort study was to investigate whether the past history of middle ear effusion has a long-term negative impact on the vestibular system in children.

Dynamics of pure tone audiometry and DPOAE changes induced by glycerol in Meniere's disease.

The purpose of this study is to follow up the dynamics of pure tone threshold and DPOAE amplitude changes induced by glycerol with reference to its activity in the inner ear. Selection was made among 38 patients with Meniere's disease for those having positive glycerol test. Pure-tone audiometry and DP-gram were performed in four series: as an initial examination before glycerol intake, 1, 2 and 3 h after.

DPOAE in estimation of the function of the cochlea in tinnitus patients with normal hearing.

Objective: The most probable place generating tinnitus in the auditory pathway is the outer hair cells (OHCs) inside the cochlea. Otoacoustic emissions are used to assess their activity. The objective of the investigation was to measure the features of distortion product otoacoustic emissions (DPOAE) in a group of tinnitus patients without hearing loss, estimate the diagnostic value of the parameters for the analysis of cochlear function in the patients, emphasizing those most useful in localizing tinnitus generators, and determine the hypothetical influence of hyperacusis and misophony on DPOAE parameters in tinnitus patients.

[Malignant neoplasm of nose and paranasal sinuses in Lower Silesia in years 1992-2001].

Unlabelled: Malignant neoplasms of the nose and paranasal sinuses occur rarely but due to late diagnosis and poor treatment effects still remain a serious problem. The aim of the study was the analysis of all nose and paranasal sinus neoplasms treated at Lower Silesia in the years 1992-2001.

Material And Methods: In the years 1992-2001 in Lower Silesia region there were 182 patients treated for malignant nose and paranasal sinus tumors.

[Diagnostic and treatment in nasal polyps of children treated in Wrocław ENT department in the years 1991-2001].

Background: Nasal polyposis is not often observed in children and usually follows general chronic diseases or disorders of cilliary structure or function and occurs mostly after 10 years of age. This is why in children clinical changes qualified as nasal polyposis should always be verified as congenital diseases or neoplasmatic changes.

Case Report: The population: of children treated in the years 1991-2001 in the Wroclaw ENT Department with initial diagnosis of nasal polyposis was presented.

[DPOAE in tinnitus patients with cochlear hearing loss considering hyperacusis and misophonia].

Unlabelled: The most probable place generating tinnitus in auditory pathway are outer hair cells (OHC) inside cochlea. To asses their activity otoacoustic emission is used. The goal of the investigation was estimation the features of otoemission DPOAE in groups with tinnitus patients with cochlear hearing loss, estimation of diagnostic value of DPOAE parameters for analysis of function of the cochlea in investigated patients emphasizing DPOAE parameters most useful in localizing tinnitus generators and estimation of hypothetic influence of hyperacusis and misophony on parameters of DPOAE in tinnitus patients with cochlear hearing loss.

[Malignant tumors of the nose and paranasal sinuses in the years 1992-2001].

On the base of retrospective analysis of 927 cases of malignant neoplasms of the nose and paranasal sinuses, diagnosed and treated in 10 clinical centers in Poland from 1992-2001, the assessment of basic epidemiological data, including the localization of tumor, and stage of local and clinical advancement of the disease at the time of diagnosis has been conducted. In analyzed period of 10 years the trends to change the mentioned above parameters has been examined. The index of morbidity in this period was constant and compareable with figures published earlier.

[RANTES expression in nasal polyps fibroblasts; spontaneously and after stimulation with lipopolisaccharides (LPS) and phytohemagglutinin (PHA)].

Introduction: According to the results of research carried out by a number of authors, one of the main mechanisms of the generation of polyps is local inflammatory processes accompanied by immune system disorders. It has recently been shown that a number of differentiation factors and inflammatory mediators may be involved in the growth of nasal polyps. RANTES is a eosinophil chemoattractant factor likely could play an important role in a chronic inflammatory response in the nasal tissue that subsequently leads to the development of nasal polyps.

[A case of bilateral oncocytomas of the submandibular gland and synchronous renal oncocytomas].

A case of 42 years-old man with bilateral big sized (12 x 5 cm and 10 x 4,5 cm) oncocytoma in submandibular glands was presented. Oncocytoma is a rare benign neoplasm observed in numerous of organs. In the case described besides submandibular glands tumours, accessory oncocytic tumours in both kidneys were diagnosed.

[Nasal glioma--case report].

Benign congenital lesions resulting from the deficient regression of neuroglial tissue in normal embryonic development are called gliomas. They are usually located in the nasofrontal region and are diagnosed in the postnatal period. They are included in the differential diagnosis of nasofrontal midline masses.

[Usefulness of imaging in the diagnosis of salivary gland diseases].

Unlabelled: The aim of this study was to evaluate the value of modern imaging modalities in the diagnosis and management of different salivary gland diseases.

Material And Methods: Material comprised of 135 patients (79 women and 56 men) at the age 14-70 (mean aged 35, 7). Ultrasonography (US) was basic examination in every case.

[Vertigo in women in menopausal period].

Unlabelled: The aim of the work was an evaluation of vestibular organ as well as static and dynamic balance condition in menopausal women. We have examined 107 women aged 46 to 55 years, 47 among them with complaints of vertigo (Group I), 30 women aged 45 to 50 years with symptoms of menopause diagnosed in Outpatient of Endocrinology Clinic (Group II) and 30 healthy women aged 45-54 (control Group). Blood concentration of sexual hormones (estradiol, LH, FSH, progesterone), sodium and potassium blood level, electronystagmography (ENG), optokinesis, eye tracking test, static and dynamic posturography and radiography of cervical part of vertebral column were applied in each case.

An evaluation of postural stability and the effects of middle-ear drainage on vestibulo-spinal reflexes of children with chronic otitis media with effusion.

Objective: Many authors agree that chronic otitis media with effusion (OME) are the main causes of vertigo and balance disturbances in children. The aim of this work was the stabilometric evaluation of postural stability and the influence of middle ear drainage on vestibulo-spinal reflexes in children with OME.

Methods: Fifteen children with OME (5-14 years old, 13 males and two females) were selected for bilateral drainage of the middle ear after conservative treatment proved ineffective.

[Experimental joint incus-stapedial injuries in scanning electron microscopy].

Because all machines and vibration devices also produce noise, the combined activities of both factors are usually examined together. The opinion dominates that vibration exerts only a weak, additionally traumatic influence on the hearing organ. The aim of our investigation was to determine the influence of long-term, whole-body vibration on the incudo-stapedial joint which integrity is indispensable for the protection of the inner ear from the effect of noise.

[DPOAE otoemission in patients with tinnitus and normal hearing].

The goal of our study was analysis of characteristic interrogation, audiometry and distortion products otoacoustic emission in patients with normal hearing and complaining of tinnitus. We examined the group of 24 ill patients with hearing threshold up till 25 dB HL and with tinnitus and the control group of 18 with no audiological complains. All the patients were made tonal audiometry and the discomfort level as well as tinnitus frequency and intensity were evaluated.

[Evaluation of glycerol test in Meniere's disease with pure tone audiometry and distortion product otoacoustic emission].

The purpose of the work was to follow up changes in the pure tone audiometry and distortion products otoacoustic emissions (DPOAE) after glycerol administration in Meniere's patients. Twenty patients with Meniere's disease and 16 with cochlear hearing loss without vestibular symptoms were subjected to the glycerol test following the complete audiological evaluation. Glycerol was administered orally 1.

Electrophysiological tests of the hearing organ in Hashimoto's disease.

Thyroid gland diseases resulting from an autoimmunological process may influence the hearing organ. The aim of this study was to assess peripheral and central parts of the hearing organ in children with Hashimoto's thyroiditis. Thirty children (mean age 14.

[Inverted papilloma of the nose and paranasal sinuses: diagnosis and treatment].

The authors present a retrospective study of 6 patients with inverted papilloma, which appeared in the material of ENT Clinic in Wrocław in years 1996-2001. In the group of treated patients, we can recognize 5 men and one woman at the age between 42 to 82. Average age amounted to 62 years.

[Role of cytokines in pathomechanism of otitis media].

Otitis media is one of the most common diseases in children. A variety if cytokines, potent inflammatory mediators, play a crucial role in the initiation and maintenance of the immunological response in otitis media. We discussed a profile of cytokines in various forms of otitis media (otitis media acute, chronic otitis media with effusion) and we underlined the differences between these types.

[Electrophysiologic tests of the auditory apparatus and vestibular organ in Usher syndrome].

Usher syndrome is a congenital autosomal dominant inherited disease characterised by hearing, balance and vision problems. The aim of the work was an evaluation of hearing and vestibular organ in the chosen group of patients with Usher syndrome diagnosed. Material consisted of 10 persons (5 males and 5 females) aged from 16 to 46 years with Usher syndrome diagnosed.

[The influence of haemodialysis on hearing organ of children with chronic renal failure].

Haemodialysis applied in terminal phase of chronic renal failure causes considerable metabolic and electrolyte disturbances within a few hours in human organism. The aim of the work was an evaluation of the influence of those disturbances on hearing organ as potential factors being responsible for perceptive hearing loss in considerable number of the patients with chronic renal failure (CRF). Examination was conducted on 20 children with CRF, aged 10-18 years.

[Two cases of hearing loss following Hashimoto disease].

Unlabelled: Hearing loss accompanies some of thyroid gland diseases especially those with hypothyroidism. Some authors state it correlates with autoimmune background of certain thyroid gland disturbances. We present two cases of patients with Hashimoto disease accompanied by fluctuating cochlear hearing loss and peripheral vestibular loss in one of the cases.

[The influence of metabolic disturbances present in diabetes mellitus type I on vestibulo-spinal reflexes in children and young adults].

Diabetic neuropathy encompasses various disturbances concerning somatic and autonomic nervous system and has significant impact on prognosis and course of diabetes mellitus. The aim of the work is an evaluation of vestibulo-spinal reflexes in children and young adults suffering from diabetes mellitus type 1. Material--95 children and young adults aged from 6 to 28 years with diabetes mellitus type 1 diagnosed.

[Epidemiology of secretory otitis media in children examined at the Otolaryngologic Clinic in Wrocław in 1996-1999].

The aim of the work was an evaluation of epidemiological factors in otitis media with effusion (OME) in children. Material consisted of 191 children treated surgically in Wroclaw ENT Clinic. The control group consisted of 95 healthy children.

[A case of Wegener's granulomatosis].

We present a case of Wegener's granulomatosis in which otitis media symptoms masked the disease in first phases. Progressive, unilateral hearing loss, almost deafness, together with facial nerve paresis allowed us to make proper diagnosis and apply therapy.