The compressive stiffness of human pediatric heads.

Head injury is a persistent and costly problem for both children and adults. Globally, approximately 10 million people are hospitalized each year for head injuries. Knowing the structural properties of the head is important for modeling the response of the head in impact, and for providing insights into mechanisms of head injury.

Tension and combined tension-extension structural response and tolerance properties of the human male ligamentous cervical spine.

Tensile loading of the human cervical spine results from noncontact inertial loading of the head as well as mandibular and craniofacial impacts. Current vehicle safety standards include a neck injury criterion based on beam theory that uses a linear combination of the normalized upper cervical axial force and sagittal plane moment. This study examines this criterion by imposing combined axial tension and bending to postmortem human subject (PMHS) ligamentous cervical spines.

Tensile mechanical properties of the perinatal and pediatric PMHS osteoligamentous cervical spine.

Pediatric cervical spine biomechanics have been under-researched due to the limited availability of pediatric post-mortem human subjects (PMHS). Scaled data based on human adult and juvenile animal studies have been utilized to augment the limited pediatric PMHS data that exists. Despite these efforts, a significant void in pediatric cervical spine biomechanics remains.

Effectiveness of Glycerol Mono-oleate as a Biosealant.

Background: The number of femoral artery catheterizations will increase over the next decade to more than 9 million worldwide. Accordingly, a new era of access site management with vascular closure techniques utilizing biologics are being developed and implemented. Glycerol mono-oleate (GMO) is one such biologic - a biodegradable compound that changes from a solid phase to a bioadhesive swollen semisolid phase when exposed to aqueous solutions and heat.

Comparative structural neck responses of the THOR-NT, Hybrid III, and human in combined tension-bending and pure bending.

This study evaluated the biofidelity of both the Hybrid III and the THOR-NT anthropomorphic test device (ATD) necks in quasistatic tension-bending and pure-bending by comparing the responses of both the ATDs with results from validated computational models of the living human neck. This model was developed using post-mortem human surrogate (PMHS) osteoligamentous response corridors with effective musculature added (Chancey, 2005). Each ATD was tested using a variety of end-conditions to create the tension-bending loads.