Publications by authors named "Lucy Carrillo"
Article Synopsis
- Aging leads to the buildup of proteins that behave like amyloid, but how these proteins form isn't fully understood.
- Researchers found that errors in messenger RNA cause amyloid-like proteins to be produced in various human cell types, including stem cells and neurons.
- These errors increase with DNA damage, which is commonly associated with aging, suggesting a connection between normal aging processes and age-related diseases.
Rheumatoid arthritis (RA) is an immune-mediated disease affecting diarthrodial joints that remains an unmet medical need despite improved therapy. This limitation likely reflects the diversity of pathogenic pathways in RA, with individual patients demonstrating variable responses to targeted therapies. Better understanding of RA pathogenesis would be aided by a more complete characterization of the disease.
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