Publications by authors named "Lucrezia Montrone"
Purpose: To analyse the morpho-functional outcomes of dexamethasone intravitreal implant (Ozurdex) injected after lens surgery in diabetic patients with coexisting cataract and macular oedema.
Methods: This is a non-randomized, perspective, single-group study on 17 eyes with a diagnosis of cataract and early and advanced diabetic macular oedema. All eyes underwent combined phacoemulsification and Ozurdex injection at the end of surgery and morpho-functional outcomes were analysed in 3 months follow-up.
Purpose: To evaluate preoperative and postoperative retinal function in patients who underwent macular surgery for idiopathic macular hole.
Design: Prospective, comparative, interventional case series.
Methods: Thirty eyes of 30 patients with idiopathic macular hole were included in the study.
Objective: To determine the impact of the regional retinal responses on cortical visually evoked responses, by evaluating the relationship between multifocal ERG (mfERG) and multifocal VEP (mfVEP), in the retinitis pigmentosa (RP) model.
Methods: MfERGs and mfVEPs were recorded from 20 typical RP patients. Response amplitude density (RAD, nV/deg(2)) and implicit time (ms) of the mfERG 1st order binary kernel (N1-P1) and mfVEP 2nd order binary kernel (P1) components were measured.
Purpose: To assess regional cone-mediated function in age-related maculopathy (ARM) by focal electroretinograms (FERGs), and to compare FERGs with morphologic changes and perimetric sensitivity at corresponding locations.
Methods: Twenty-six ARM patients and 12 age-matched controls were evaluated. FERGs were elicited by either a central (0-2.
Background: Epigallocatechin-gallate (EGCG) is a powerful antioxidant with suggested neuroprotective action. The aim of this study was to evaluate the effect of short-term supplementation of EGCG on inner retinal function in ocular hypertension (OHT) and open-angle glaucoma (OAG).
Methods: Eighteen OHT and 18 OAG patients (perimetric mean deviation: >-10 dB) were randomly assigned to assume oral placebo or EGCG over a 3-month period in a randomized, placebo-controlled, double-blind, cross-over design clinical trial (clinicaltrials.
Purpose: To examine longitudinally optic disc structure and inner retinal function in treated ocular hypertension (OHT).
Materials And Methods: A morphometric (Heidelberg Retina Tomograph, HRT) and functional (steady-state pattern electroretinogram, PERG) evaluation of 27 OHT patients treated with topical beta-blockers and/or prostaglandin analogues and prospectively followed over a 24 +/- 6 month period.
Results: Compared with baseline, mean final PERG amplitude tended to increase (p < 0.
Background: Pattern electroretinogram (PERG) and optical coherence tomography (OCT) represent objective probes to investigate respectively the function of retinal ganglion cells and their structure as retinal nerve fiber layer (RNFL) thickness. We examined interindividual (II) correlations of PERG amplitude and RNFL thickness, as well as correlations between interocular (IO) differences in both measures, in ocular hypertension (OHT) and early glaucoma (EG) patients.
Methods: Thirty-one OHT, 34 EG (mean deviation: -1 to -6 dB) and 16 age-matched controls were examined in both eyes.
Purpose: To evaluate regional cone system function after uncomplicated retinal detachment (RD) surgery, by recording focal electroretinograms (FERGs) from the central and paracentral regions of the posterior pole.
Methods: FERGs in response to either a central (eccentricity: 0-2.25 deg) or a paracentral annular (2.