Publications by authors named "Lucrezia Grillone"
Background: Patients undergoing allogeneic stem-cell transplantation (allo-SCT) have reduced responses to vaccines due to immunosuppressive status linked to GvHD prophylaxis and treatment. In our study, we compared humoral responses to anti-SARS-CoV-2 mRNA vaccine, and infection onset, according to patients and transplant features; we also evaluated cellular response in patients without seroconversion.
Methods: We tested antibodies titer after second and third vaccine doses.
Background & Aims: A strategy to improve the low rate of anti-SARS-CoV-2 mRNA vaccine-induced immunogenicity in liver transplant recipients (LTs) is urgently needed.
Methods: We analysed the rate of positive (≥0.8 U/ml) anti-SARS-CoV-2 receptor domain-binding protein (RBD) antibody response 2 months after a third dose of the BNT16b2 vaccine in 107 LTs who completed the second vaccine dose 7 months earlier.
Background & Aims: The long-term immunogenicity of anti-SARS-CoV-2 vaccines in liver transplant (LT) recipients is unknown. We aimed to assess the long-term antibody response of the Pfizer-BioNTech® BNT162b2 vaccine in LT recipients compared to controls.
Methods: LT recipients underwent anti-SARS-CoV-2 anti-receptor-binding domain protein IgG (anti-RBD) and anti-nucleocapsid protein IgG antibody (anti-N) measurements at the first and 1, 4 and 6 months after the second vaccination dose.
Context: Health promotion (HP) and clinical risk management (CRM) topics are seldom discussed during medical school lessons. Peer-assisted learning (PAL) has long occurred informally in medical education, and interest in this method has recently grown, as it is considered a valuable technique for both tutors and tutees.
Aims: The aim was to evaluate the impact of HP and CRM PAL intervention on medical students' (tutees) knowledge level.
Article Synopsis
- The study analyzed incident reporting trends over 6 years at a large Italian academic hospital, focusing on how different professions report incidents and their attitudes toward self-reporting.
- Doctors' reporting rates significantly increased from 2010 to 2015, reaching 0.67, compared to nurses who had a stable rate of 0.40, despite nurses being more likely to self-report severe incidents.
- The overall decrease in patient complaints and work accidents suggests a potential correlation with better reporting practices, highlighting the importance of monitoring incident reporting as a measure of patient safety.