Publications by authors named "Lucrezia Biagiotti"

Background: Lipoprotein(a) [Lp(a)] is associated with increased cardiovascular risk, but its influence on plaque characteristics at optical coherence tomography (OCT) evaluation is not fully understood.

Aims: This study seeks to explore the impact of Lp(a) levels on plaque morphology as assessed by OCT in a very high-risk subset of patients.

Methods: Consecutive patients admitted for acute coronary syndrome (ACS) and undergoing OCT-guided percutaneous coronary intervention (PCI) at a large tertiary care center between 2019 and 2022 were deemed eligible for the current analysis.

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Article Synopsis
  • - This study assessed if sodium-glucose cotransporter-2 inhibitors (SGLT2-i) can protect against contrast-induced acute kidney injury (CI-AKI) in heart failure patients undergoing procedures using iodinated contrast.
  • - Researchers divided participants into those using SGLT2-i and those not, measuring the occurrence of CI-AKI, overall mortality, and the need for renal therapy during hospitalization.
  • - Results showed lower CI-AKI rates in SGLT2-i users (9.3%) compared to non-users (27.3%), and the SGLT2-i group had no need for continuous renal replacement therapy, suggesting that SGLT2-i therapy offers a protective benefit in this context. *
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