Diastolic dysfunction, hypertrophy and hypertension ventricular-arterial uncoupling treatment.

The aim of the study was to evaluate hypertension treatment effects on mechanical efficiency of the cardiovascular system and cardiac reverse remodeling in hypertensive patients. This is an observational prospective study, consecutive hypertension patients. Left ventricle mass index measured by Devereux 2D method and diastolic function following the Guidelines from the American Society of Echocardiography and the European Association of Cardiovascular Imaging.

Ventricular-Arterial Uncoupling and Hypertension Mediated Diastolic Dysfunction.

Introduction: The increase in the pulsatile component of left ventricle afterload is suspected to cause a mismatch between the left ventricle (LV) and the vascular tree.

Aim: To demonstrate that ventricular-arterial uncoupling is frequently present in the development of LV hypertrophy (H) and diastolic dysfunction (DD) in hypertension (HBP).

Methods: Observational study, HBP patients with ejection fraction > 54%.

Medium to Long Term Follow-Up of Treated Hypertensive Mediated Heart Disease.

Introduction: Hypertensive mediated heart disease is the consequence of anatomical and functional changes in cardiovascular system. The benefits on left ventricular (LV) diastolic impairment and remodeling of hypertension treatment are well established.

Aim: To evaluate LV structure, systolic and diastolic function of treated hypertensive patients on a medium to long term follow-up.

Functional Organ Damage in Cardiovascular Low Risk Patients with High Central Aortic Pressure.

Background: The loss of the viscoelastic properties of central arteries independently of blood pressure loads could stimulate the development of left ventricular hypertrophy and dysfunction, renal failure, or cerebral vascular injury.

Objective: The aim of the present study is to determine if an elevated systolic aortic pressure is a marker of more frequent target organ damage (TOD) in hypertensive low cardiovascular risk (CVR) patients.

Methods: Hypertensive non treated consecutive patients (p) assisted at first visit in a specialized center with a CVR according to WHO Americas B area score less than 10 % were included.