Short term effects of extremely low irradiance photobiomodulation on retinal function, in age related macular degeneration.

Background: recently much studies evidenced the potential role of photo-biomodulation (PBM) in patients affected by Age-related Macular Degeneration (AMD). We designed a new wearable device for self-medication that employs the same broadband red light described in literature, but with extremely low irradiance.

Aim: to demonstrate the safety and effectiveness of low-fluence light stimulations emitted by a LED source with appropriate wavelengths through our new device in improving short-term visual function in patients affected by severe non neovascular AMD.

Nutritional physiology and body composition changes during a rapid ascent to high altitude.

Exposure to high altitude might cause the body to adapt with negative energy and fluid balance that compromise body composition and physical performance. In this field study involving 12 healthy adults, sex-balanced, and aged 29 ± 4 years with a body mass index of 21.6 ± 1.

Clinical features and health-threatening conditions of the trek to Capanna Margherita.

Background: Since trips to high altitude have become popular, reports on clinical and environmental characteristics during expeditions to popular destinations are needed.

Methods: A group of 15 healthy adults was monitored during a trek to Capanna Margherita (4556 m). A hypoxic stress test was applied before the expedition started.

Stickler syndrome associated with epilepsy: report of three cases.

Unlabelled: Stickler syndrome is a genetically heterogeneous collagenopathy characterized by auditory, ocular, musculoskeletal, and orofacial abnormalities. Stickler syndrome type 1 typically presents ophthalmologic involvement and is due to heterozygous defects of the COL2A1 gene, that have been also identified as the molecular cause of a continuous spectrum of different disorders mainly affecting the cartilage and bone (i.e.

Long-term outcome of epilepsy in patients with Prader-Willi syndrome.

Prader-Willi syndrome is a multisystemic genetic disorder that can be associated with epilepsy. There is insufficient information concerning the clinical and electroencephalographic characteristics of epilepsy and the long-term outcome of these patients. The aim of this study is to describe seizure types, electroencephalographic patterns and long-term seizure outcome in Prader-Willi syndrome patients suffering from epilepsy.

Postoperative finding in the intraoperative floppy-iris syndrome.

We describe a postoperative finding discovered before surgery in the second eye of a patient who had intraoperative floppy-iris syndrome (IFIS). Recognizing the risk for IFIS is important to anticipate and manage the syndrome and ensure successful cataract surgery. Obtaining the right information about the past and present intake of alpha-blockers is mandatory.

Retinal nerve fiber layer and macular thickness in adolescents with epilepsy treated with valproate and carbamazepine.

Purpose: To evaluate retinal nerve retinal nerve fiber layer (RNFL) and macular thickness by using optical coherence tomography (OCT) in epileptic adolescents before and during monotherapy with valproic acid (VPA) and carbamazepine (CBZ).

Methods: We examined prospectively 45 epilepsy patients with partial and generalized epilepsy. The patients were evaluated before the beginning of therapy and after 1 year of VPA or CBZ monotherapy.