Publications by authors named "Lucio Huebra"
Article Synopsis
- Anti-IgLON5 disease is a newly identified neurological disorder characterized by autoimmunity and neurodegeneration, with a substantial prevalence of abnormal movements that have been largely overlooked.
- In a study of 72 patients, 87% exhibited at least one movement disorder, with gait and balance issues being the most common, followed by chorea and bradykinesia.
- The majority of patients experienced additional symptoms such as sleep disturbances, bulbar dysfunction, and cognitive impairment, and many showed significant improvement in movement disorders after receiving immunotherapy treatment.
Study Objectives: To the best of our knowledge, there has not as yet been any study on the effects of the COVID-19 pandemic on patients with narcolepsy, in particular, in relation to its impact on sleep schedules, symptoms, the need for medication, work, income, and quality of life. This study therefore aimed to explore these factors and their possible influence on sleep, circadian timing, and narcolepsy symptoms during the pandemic.
Methods: Patients with narcolepsy who had been in quarantine for at least 3 months completed a 36-question online survey.
Sleep Disorders in Hereditary Ataxias.
Curr Neurol Neurosci Rep
July 2019
Purpose Of Review: In this review, we aim to describe the main sleep disorders observed in patients with different forms of hereditary ataxias and discuss the main pathophysiological mechanisms.
Recent Findings: Several pathological studies have demonstrated that the degenerative process in patients with hereditary ataxias may involve not only the cerebellum, but also other areas of the nervous system, and explain noncerebellar symptoms, such as sleep disorders. Hereditary ataxias are neurodegenerative disorders with heterogeneous genetic and clinical presentation.