Publications by authors named "Lucimeire N Carvalho"

Article Synopsis
  • * Cornea xenotransplantation using porcine corneas is a potential solution due to the cost-effectiveness and biological compatibility, but there are ethical issues and immune rejection concerns that need to be addressed.
  • * Recent advancements in genetic engineering and new immunosuppressive techniques are showing promise in increasing the success rate of porcine corneal transplants, highlighting the need for ongoing research to improve safety and effectiveness.
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Background/aims: Pregnancy is characterized by vasodilatation and increased glomerular filtration rate (GFR), despite overstimulation of the renin angiotensin system (RAS). The mesangial cells (MCs) influences GFR and when cultured from pregnant rats displays refractoriness to Ang II. We evaluated the role of relaxin (RLX) and its receptor (RXFP1), nitric oxide (NO) and the AT2 receptor in this response.

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The birdseed Phalaris canariensis (Pc) is popularly used as an antihypertensive agent. The aqueous extract of Pc (AEPc) was administered in adult normotensive Wistar rats and spontaneously hypertensive rats (SHR) and in prehypertensive young SHR (SHR(Y), 3 weeks old). Animals received AEPc (400 mg·kg(-1)·day(-1), by gavage) for 30 days, then groups were divided into 2 subgroups: one was treated for another 30 days and the other received water instead of AEPc for 30 days.

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