Microplastics have been detected in several aquatic organisms, especially bivalves such as clams, oysters, and mussels. To understand the ecotoxicological implication of microplastic accumulation in biota, it is crucial to investigate effects at the physiological level to identify knowledge gaps regarding the threat posed to the environment and assist decision-makers to set the necessary priorities. Typically, xenobiotics elicit an overproduction of reactive oxygen species in organisms, resulting in oxidative stress and cellular damage when not combated by the antioxidative system.
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