Cyclosporine A - Induced gingival overgrowth and proliferating cell nuclear antigen expression in experimental periodontitis.

Unlabelled: The most important microscopic characteristic of Cyclosporine A-induced gingival overgrowth is fibroepithelial hyperplasia.

Objective: The objective was to investigate the influence of previous exposure to Cyclosporine A over gingival epithelium in experimental periodontitis in rats.

Methods: Twenty Wistar rats with 12 weeks-old were divided into four groups with 5 animals each: Control Group (CG); Cyclosporine Group (CsAG); Ligature group (LG) and Cyclosporine and Ligature Group (CsALG).

Medical and Periodontal Clinical Parameters in Patients at Different Levels of Chronic Renal Failure.

. To assess the clinical periodontal and medical parameters in patients with chronic renal failure (CRF) at different levels of renal disease. .

Salivary markers in patients with chronic renal failure.

Introduction: Chronic renal failure (CRF) is a progressive loss of renal function over a period of months or years. The major function of the kidneys is the removal of metabolic waste products, electrolytes and water. When this function is impaired, systemic changes, oral complications and alterations in salivary composition may occur.

Previous exposure to Cyclosporine A and periodontal breakdown in rats.

Objective: The aim of this study was to evaluate the influence of previous exposure to Cyclosporine A (CsA) on experimental periodontitis in rats.

Design: Forty rats were divided into 4 groups: Control (CON); Cyclosporine A (CsA), which received daily doses of 10mg/kg CsA; Ligature (LIG), which received an insertion of a cotton ligature around the mandibular 1st molar at day 30; and Ligature and CsA (CsAL), which were treated with CsA and the cotton ligature. At day 60 of the experiment, animals were sacrificed, and groups were compared with regards to Alkaline Phosphatase (AP) activity, gingival overgrowth, periodontal bone support (PBS), bone resorption at furcation ligament area (LA) and TRAP+ cells.

Influence of alcohol consumption on alveolar bone level associated with ligature-induced periodontitis in rats.

Alcohol consumption is a risk indicator for periodontal disease. The purpose of this study was to morphometrically evaluate the influence of alcohol consumption on alveolar bone level associated with ligature-induced periodontitis in rats. Thirty-six female rats (Wistar, 120 days-old) were randomly divided into three groups that received a daily administration of a water diet (control, n = 12), a 10% alcohol diet (10% ethanol, n = 12) or a 20% alcohol diet (20% ethanol, n = 12).

Histological analysis of effects of 24% EDTA gel for nonsurgical treatment of periodontal tissues.

The aim of this study was to investigate, by means of histological and histomorphometric analysis, the effects of 24% ethylenediaminetetraacetic acid (EDTA) gel in periodontal tissue when used in combination with conventional periodontal treatment. Periodontitis was induced in the 2nd upper left permanent molars of 45 male Wistar rats by means of ligature. After 5 weeks, this was removed and debridement was performed.

The effect of alcohol consumption on periodontal bone support in experimental periodontitis in rats.

Objective: The aim of this study was to evaluate the effect of the alcohol consumption on the periodontal bone support (PBS) in experimental periodontitis in rats.

Materials And Methods: Sixty-three male rats were divided into seven groups: G1 (control); G2 (10% ethanol); G3 (nutritional control of G2); G4 (20% ethanol); G5 (nutritional control of G4); G6 (30% ethanol) and G7 (nutritional control of G6). The groups G3, G5 and G7 received controlled diets with equivalent caloric amounts to those consumed in G2, G4 and G6 respectively, with the ethanol replaced by sucrose.

Assessment of the "golden proportion" in agreeable smiles.

Objectives: The aim of this study was to determine the prevalence of the "golden proportion" in individuals presenting agreeable smiles.

Method And Materials: Two hundred sixty university students aged 18 to 30 years of age (130 subjects of each gender) with maxillary incisors, canines, and premolars presenting anatomic integrity were evaluated. Agreeable smiles were considered to be those displaying at least second premolars; revealing no gingival recession in the smile area; having interdental papillae that filled all interdental spaces and were not hyperplastic; showing less than 3 mm of the maxillary gingiva; displaying the line of the lower lip parallel to the incisal line of the maxillary teeth and also to an imaginary line linking the contact points of these teeth; and, finally, presenting symmetry upon examination.

Longitudinal clinical evaluation of adjunct minocycline in the treatment of chronic periodontitis.

Background: The clinical benefits of minocycline in combination with thorough scaling and root planing (SRP) have been examined in multicenter studies. The aim of this longitudinal investigation was to evaluate the clinical response to scaling and root planing combined with the use of locally delivered minocycline microspheres for 720 days in individuals with advanced chronic periodontitis.

Methods: A total of 26 individuals aged 26 to 69 years (mean: 46.