Publications by authors named "Lucila Bizari Fernandes do Prado"

Study Objectives: The COVID-19 pandemic has created unprecedented levels of stress and anxiety, which has a profound effect on sleep quality. However, limited data are available on the sleep quality of medical residents who work directly with patients infected with SARS-CoV-2. As sleep is a crucial brain state, our goal is to know the sleep quality of these medical residents.

View Article and Find Full Text PDF
Article Synopsis
  • * She experienced sleeplessness, headaches, dizziness, and motor/sensory deficits, with a history of AIDS and irregular antiretroviral therapy.
  • * The findings suggest that structural abnormalities in the brain, particularly in the left nucleocapsular area, may contribute to sleep state misperception, as indicated by previous research on related brain activation patterns.
View Article and Find Full Text PDF
Article Synopsis
  • * Conducted in Cássia dos Coqueiros, Brazil, the research involved 383 participants aged 5-17, comparing those with RLS to a matched control group without the condition.
  • * Findings showed a 1.9% prevalence of RLS in the sample, with affected individuals reporting poorer sleep quality and lower quality of life scores compared to the controls.
View Article and Find Full Text PDF

Study Objectives: To report two female patients with paraneoplastic cerebellar degeneration (PCD) related to breast cancer that presented with rapid eye movement-sleep behavior disorder (RBD) and improved sleep symptoms with immunotherapy.

Methods: The two patients were evaluated through clinical scale and polysomnography before and after therapy with intravenous immunoglobulin.

Results: RBD was successfully treated with immunotherapy in both patients.

View Article and Find Full Text PDF

Spinocerebellar ataxias (SCA) are autosomal dominant neurodegenerative disorders that affect the cerebellum and its connections, and have a marked clinical and genetic variability. Machado-Joseph disease (MJD) or spinocerebellar ataxia type 3 (SCA3)--MJD/SCA3--is the most common SCA worldwide. MJD/SCA3 is characterized classically by progressive ataxia and variable other motor and non-motor symptoms.

View Article and Find Full Text PDF

The Consensus on restless legs syndrome is an effort of neurologists from several Brazilian states, which tirelessly reviewed the literature of recent years in search of evidence, both in regard to diagnosis and treatment, according to the Oxford Centre for Evidence-based Medicine.

View Article and Find Full Text PDF
Article Synopsis
  • Insomnia is characterized by difficulty in falling asleep, staying asleep, or achieving restorative sleep, impacting both psychological and physiological well-being.
  • The review highlights various factors contributing to insomnia, including cognitive components like worry, behavioral conditioning, and physiological changes such as increased heart rate and muscle tone.
  • It also discusses neurobiological perspectives, including the inhibition of wakefulness and hyperarousal, and presents non-pharmacological interventions to address insomnia's multifaceted nature.
View Article and Find Full Text PDF

Objective: We aimed to compare the academic performance of children with and without symptoms of sleep disorders (SSD).

Methods: We distributed 5400 questionnaires (Sleep Disturbance Scale for Children [SDSC], Brazilian version) to 7- to 10-year-old children at public elementary schools in São Paulo, Brazil. We analyzed the academic grades of Portuguese (Port) and Mathematics (Math) in 2384 children (1224 girls; 51%).

View Article and Find Full Text PDF
Article Synopsis
  • The study aimed to compare the craniofacial measurements of mouth-breather boys and girls to those of obstructive sleep apnea syndrome (OSAS) patients.
  • The research involved analyzing lateral cephalometric radiographs of 144 children aged 7-14, revealing that boys and girls who breathe through their mouths had similar craniofacial features, unlike nose-breathers who showed expected gender differences.
  • The findings suggest that mouth-breathers, regardless of gender, exhibit similar craniofacial morphology indicative of changes associated with OSAS, implying that oral breathing could lead to a uniform impact on facial structure.
View Article and Find Full Text PDF
Article Synopsis
  • The study focuses on sleep disorders in patients with spinocerebellar ataxia type 3 (Machado-Joseph disease), specifically restless legs syndrome and rapid eye movement sleep behavior disorder, and examines the link with dopamine transporter (DAT) densities.
  • Twenty-two MJD patients and twenty healthy subjects participated, undergoing clinical evaluations, polysomnography, and DAT imaging via SPECT.
  • Results indicated that MJD patients had significantly lower DAT densities compared to controls, but no correlation was found between DAT levels and sleep disorders, suggesting other dopamine pathways may play a role in MJD-related sleep issues.
View Article and Find Full Text PDF
Article Synopsis
  • The study focused on children with adenotonsillar hypertrophy and abnormal craniofacial morphology, investigating the link between sleep disordered breathing and mouth-breathing habits.
  • A group of 27 children (15 mouth breathers and 12 nose breathers) underwent polysomnographic assessments and cephalometric measurements to analyze aspects like sleep efficiency and airway space.
  • Results indicated that mouth breathers had more significant sleep issues, including snoring and a higher apnea-hypopnea index, and exhibited distinct craniofacial characteristics compared to nose breathers, highlighting the need for sleep evaluations in at-risk children.
View Article and Find Full Text PDF

Objective: To determine whether mouth breathing children present the same cephalometric patterns as patients with obstructive sleep apnea syndrome (OSAS).

Method: Cephalometric variables were traced and measured on vertical lateral cephalometric radiographs. The cephalometric measurements of 52 mouth and 90 nose breathing children were compared with apneic patients.

View Article and Find Full Text PDF

Mandibular repositioning appliances (tMRAs) designed with a titratable mechanism are effective to treat obstructive sleep apnea syndrome (OSAS) but are not widely used, although many studies have proven their value. The aim of the present study was to evaluate the efficacy of tMRAs in the treatment of OSAS on the criteria of the American Academy of Sleep Medicine (AASM; apnea/hypopnea index [AHI] < 5). Three hundred consecutive patients with a polysomnographic diagnosis of OSAS were referred for treatment with tMRAs between 2000 and 2003.

View Article and Find Full Text PDF

Introduction: Intraoral mandibular repositioner appliances (IOMRAs) are designed to enlarge pharyngeal airway space advancing the mandible and increasing genioglossus tone during sleep. Obstructive sleep apnea syndrome (OSAS) treatment with IOMRAs is beneficial, but there is a lack of studies in the literature defining the target population more inclined to respond to this treatment.

Methods: We contacted by telephone 188 previously treated patients with IOMRA, detecting 20 not improved patients (Study Group).

View Article and Find Full Text PDF
Article Synopsis
  • Obstructive sleep apnea syndrome (OSAS) significantly affects patients' quality of life, with various treatments available, but there's often a focus on apnea index rather than overall well-being.
  • * The study evaluated 11 male patients aged 34 to 63 with mild to moderate OSAS, using a questionnaire to assess quality of life before and after four weeks of treatment with an individual mandibular repositioner (IOMR).
  • * Results showed notable improvements with 45.5% of patients experiencing excellent quality of life enhancement and 90.9% seeing significant symptom relief after IOMR treatment.*
View Article and Find Full Text PDF

Unlabelled: Sleep is basic for physical and cognitive development and some studies have suggested that there may be an association between sleep disorders (SD) and cognitive dysfunction (CD) in children. Little is known, however, about SD and cognition in 7-10-year-old children, a fact that motivated the present study.

Method: We applied an SD questionnaire in 1180 children, 547 with SD and 633 without SD (CG), to assess cognition with a screening test (Bender Visual Motor Gestalt Test - BT).

View Article and Find Full Text PDF

Unlabelled: Convulsions triggered by fever are the most common type of seizures in childhood, and 20% to 30% of them have recurrence. The prophylactic treatment is still controversial, so we performed a systematic review to find out the effectiveness of continuous phenobarbital and intermittent diazepam compared to placebo for febrile seizure recurrence.

Method: Only randomized, double-blind, placebo-controlled trials were analyzed.

View Article and Find Full Text PDF

Unlabelled: The personality is the way people express themselves inside the environment they live. Sleep, quality or quantity, is a way of this physical and psychological expression of well being. Psychological factors, associated with psychophysiological insomnia (PPI) suggest an exaggerated perception of the difficulties to fall asleep.

View Article and Find Full Text PDF