Publications by authors named "Lucie Percevault"
Cold-Spray Ionization mass spectrometry (CSI-MS) that can be compared to an electrospray ionization (ESI) source acting with a nebulizing gas cooled by liquid nitrogen is used for analyzing reline as Deep Eutectic Solvent (DES). The association of cholinium chloride salts with urea molecules is evidenced in negative CSI-MS through the chloride adduct formation. The structure of the supramolecular assemblies forming the reline ions that are observed on CSI mass spectra is rationalized by chemical quantum calculations.
View Article and Find Full Text PDFWe have performed small-angle neutron scattering in a momentum transfer range (0.05 < < 0.5 Å) to study long-range order and concentration fluctuations in deep eutectic solvents (DESs) and their aqueous solutions.
View Article and Find Full Text PDFArticle Synopsis
- Electron transfer kinetic rate constants were measured in Ethaline (a deep eutectic solvent) for ferrocene/ferrocenium and ferrocyanide/ferricyanide redox couples, showing that they are only slightly lower than those in traditional solvents like acetonitrile and water, approximately 50% or less.
- In comparison, electron transfer rates in ionic liquids are significantly slower, about 100 times lower than in classical solvents.
- The findings are analyzed using Marcus Theory, specifically focusing on the solvent relaxation time and its impact on adiabatic electron transfer processes.
In the field of nicotinic acetylcholine receptors (nAChRs), recognized as important therapeutic targets, much effort has been dedicated to the development of nicotinic analogues to agonize or antagonize distinct homo- and heteropentamers nAChR subtypes, selectively. In this work we developed di- and heptavalent nicotinic derivatives based on ethylene glycol (EG) and cyclodextrin cores, respectively. The compounds showed a concentration dependent inhibition of acetylcholine-induced currents on α7 nAChR expressed by Xenopus oocytes.
View Article and Find Full Text PDF