Publications by authors named "Lucie Della Schiava"

Background: Retinal artery occlusion (RAO) may lead to irreversible blindness. For acute RAO, intravenous thrombolysis (IVT) can be considered as treatment. However, due to the rarity of RAO, data about IVT safety and effectiveness is limited.

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Article Synopsis
  • The study examined how treatment delays affect the outcomes of intravenous thrombolysis (IVT) before mechanical thrombectomy (MT) in patients who suffered a stroke.
  • Researchers analyzed data from the SWIFT-DIRECT trial involving 408 patients, comparing outcomes between those receiving IVT+MT and those undergoing MT alone, focusing on functional independence and safety outcomes.
  • Results showed no significant interaction between treatment delays and the benefits of IVT, but there was some indication that shorter in-hospital delays might lead to better outcomes, suggesting the need for further investigations in future studies.
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Article Synopsis
  • The study looked at whether doing a procedure called thrombectomy by itself is just as good as doing thrombectomy with a medicine called alteplase for patients who have a stroke caused by a blocked blood vessel.
  • Researchers in Europe and Canada tested this by randomly assigning stroke patients to either just thrombectomy or thrombectomy plus alteplase.
  • They wanted to see if the patients who only had thrombectomy would have similar recovery outcomes to those who had both treatments, and they kept track of how well everyone was doing over 90 days.
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Introduction: I ntracranial vertebral dissections have polymorphs clinical presentations and can lead to haemorrhagic complications if they are intracranial. We here describe a case of a thrombosed dissecting aneurysm of postero-inferior cerebellar artery (PICA) revealed by a Wallenberg syndrome preceded by headaches.

Case: A 23-year-old patient, without neurological or vascular past medical history, was admitted for dizziness preceded by headache.

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Objectives: Pre-stroke dependency (PSD) is associated with poor outcome after stroke. The aim of the study was to evaluate the clinical outcomes and safety of mechanical thrombectomy (MT) in pre-stroke dependent patients compared to pre-stroke independent patients.

Material And Methods: We included consecutive patients with anterior circulation acute ischaemic stroke related to large vessel occlusion (AIS-LVO), treated by MT between January 1 2015 and July 1 2018 in our single comprehensive stroke center.

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Background: The epileptogenicity of recombinant tissue-plasminogen activator (rt-PA) has been suggested, but seizures were not evaluated in randomised controlled trials.

Objective: To evaluate whether rt-PA was associated with early seizures in a cohort of consecutive patients with cerebral ischaemia.

Method: We included consecutive adults with ischaemic stroke due to large-vessel occlusion from the North-of-France stroke network selected for a mechanical thrombectomy (MT).

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Background: Patients treated at off-hours for acute conditions have increased mortality rates. This effect has been poorly evaluated in patients treated by mechanical thrombectomy (MT).

Objective: This study aimed at comparing outcomes between patients treated at off-hours and at working hours by MT for acute stroke due to large-vessel occlusion in the anterior circulation, in a well-organised network.

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