The Neural Specificity of Interference Resolution in Phonological, Semantic, and Visual Domains at Different Ages.

The question of whether cognitive control is specific to certain domains or domain-general remains an extensively debated question at both cognitive and neural levels. This study examined the neural substrates associated with resistance to interference (RI) in phonological, semantic, and visual domains by using strictly matched tasks and determining the domain-general or domain-specific manner in which aging affects the neural substrates associated with RI. In an fMRI experiment, young and older participants performed a similarity judgment task with phonological, semantic, or visual interference buildup.

From long-term to short-term: Distinct neural networks underlying semantic knowledge and its recruitment in working memory.

Although numerous studies suggest that working memory (WM) and semantic long-term knowledge interact, the nature and underlying neural mechanisms of this intervention remain poorly understood. Using functional magnetic resonance imaging (fMRI), this study investigated the extent to which neural markers of semantic knowledge in long-term memory (LTM) are activated during the WM maintenance stage in 32 young adults. First, the multivariate neural patterns associated with four semantic categories were determined via an implicit semantic activation task.

Enhancing rhythmic temporal expectations: The dominance of auditory modality under spatial uncertainty.

To effectively process the most relevant information, the brain anticipates the optimal timing for allocating attentional resources. Behavior can be optimized by automatically aligning attention with external rhythmic structures, whether visual or auditory. Although the auditory modality is known for its efficacy in representing temporal information, the current body of research has not conclusively determined whether visual or auditory rhythmic presentations have a definitive advantage in entraining temporal attention.

Evidence of a positive effect of verbal cumulative rehearsal on serial order working memory, as early as 4 years old.

The use of a verbal rehearsal strategy (repeating the items to be remembered to oneself in serial order) has been identified as a key factor in explaining working memory (WM) development. However, the debate remains open with regard to the age at which children are able to use it, and the actual benefits of using such a strategy. Numerous methodological constraints to identify WM strategies limit the interpretation of current findings reported in the literature.

Neural evidence for a separation of semantic and phonological control processes.

There remain major doubts about the nature and domain specificity of inhibitory control processes, both within and between cognitive domains. This study examined inhibitory processes within the language domain, by contrasting semantic versus phonological inhibitory control. In an fMRI experiment, elderly participants performed phonological and semantic inhibitory control tasks involving resistance to highly or weakly interfering stimuli.

The Neural Representation of Ordinal Information: Domain-Specific or Domain-General?

Ordinal processing allows for the representation of the sequential relations between stimuli and is a fundamental aspect of different cognitive domains such as verbal working memory (WM), language and numerical cognition. Several studies suggest common ordinal coding mechanisms across these different domains but direct between-domain comparisons of ordinal coding are rare and have led to contradictory evidence. This fMRI study examined the commonality of ordinal representations across the WM, the number, and the letter domains by using a multivoxel pattern analysis approach and by focusing on triplet stimuli associated with robust ordinal distance effects.

Do serial order short-term memory and long-term learning abilities predict spelling skills in school-age children?

Compared to most human language abilities, the cognitive mechanisms underlying spelling have not been as intensively investigated as reading and therefore remain to this day less well understood. The current study aims to address this shortcoming by investigating the contribution of serial order short-term memory (STM) and long-term learning (LTL) abilities to emerging spelling skills. Indeed, although there are several reasons to assume associations between serial order memory and spelling abilities, this relationship has hardly been investigated empirically.

Toward an integrative model accounting for typical and atypical development of visuospatial short-term memory.

The origin of visuospatial short-term memory (STM) impairment is poorly investigated and is generally considered to be the result of a more global visuospatial deficit. However, previous studies suggest an important influence of two elements on performance in visuospatial STM tasks, the mode of presentation (i.e.

The contribution of serial order short-term memory and long-term learning to reading acquisition: A longitudinal study.

There is increasing evidence for an association between both serial order short-term memory (STM) and the long-term learning (LTL) of serial order information and reading abilities. In this developmental study, we examined the hypothesis that STM for serial order supports online grapheme-to-phoneme conversion processes during the initial stages of reading acquisition, whereas the LTL of serial order serves reading abilities at later stages, when reading starts to rely on more stable, long-term orthographic representations. We followed a sample of 116 French-speaking children from first (Time 1 [T1]) grade of primary school through second (Time 2 [T2]) and third (Time 3 [T3]) grade.

The developmental neural substrates of Hebb repetition learning and their link with reading ability.

Hebb repetition learning is a fundamental learning mechanism for sequential knowledge, such as language. However, still little is known about its development. This fMRI study examined the developmental neural substrates of Hebb repetition learning and its relation with reading abilities in a group of 49 children aged from 6 to 12 years.

Magnitude processing in populations with spina-bifida: The role of visuospatial and working memory processes.

People with Spina Bifida usually experience difficulties with mathematics. In a series of other developmental disorders, a magnitude processing deficit was considered to be the main source of subsequent difficulties in mathematics. The processing of magnitude could be numerical (which is the larger number) or non-numerical such as spatial (e.

Neural Patterns in Linguistic Cortices Discriminate the Content of Verbal Working Memory.

An influential theoretical account of working memory (WM) considers that WM is based on direct activation of long-term memory knowledge. While there is empirical support for this position in the visual WM domain, direct evidence is scarce in the verbal WM domain. This question is critical for models of verbal WM, as the question of whether short-term maintenance of verbal information relies on direct activation within the long-term linguistic knowledge base or not is still debated.

The developmental neural substrates of item and serial order components of verbal working memory.

Behavioral and developmental studies have made a critical distinction between item and serial order processing components of verbal working memory (WM). This functional magnetic resonance imaging (fMRI) study determined the extent to which item and serial order WM components are characterized by specialized neural networks already in young children or whether this specialization emerges at a later developmental stage. Total of 59 children aged 7-12 years performed item and serial order short-term probe recognition tasks in an fMRI experiment.

The effect of visual arrangement on visuospatial short-term memory: Insights from children with 22q11.2 deletion syndrome.

Recent models of visuospatial (VSSP) short-term memory postulate the existence of two dissociable mechanisms depending on whether VSSP information is presented simultaneously or sequentially. However, they do not specify to what extent VSSP short-term memory is under the influence of general VSSP processing. This issue was examined in people with 22q11.

Serial order working memory and numerical ordinal processing share common processes and predict arithmetic abilities.

Recent studies have demonstrated that both ordinal number processing and serial order working memory (WM) abilities predict calculation achievement. This raises the question of shared ordinal processes operating in both numerical and WM domains. We explored this question by assessing the interrelations between numerical ordinal, serial order WM, and arithmetic abilities in 102 7- to 9-year-old children.

Evidence of the impact of visuo-spatial processing on magnitude representation in 22q11.2 microdeletion syndrome.

The influence of visuo-spatial skills on numerical magnitude processing is the subject of a long-standing debate. As most of the numerical and non-numerical magnitude abilities underpinning mathematical development are visual by nature, they are often assessed in the visual modality, thereby confusing visuo-spatial and numerical processing. In order to assess the influence of visuo-spatial processing on numerical magnitude representation, we examined magnitude processing in patients with 22q11.

The role of short-term memory and visuo-spatial skills in numerical magnitude processing: Evidence from Turner syndrome.

Most studies on magnitude representation have focused on the visual modality with no possibility of disentangling the influence of visuo-spatial skills and short-term memory (STM) abilities on quantification processes. This study examines this issue in patients with Turner syndrome (TS), a genetic condition characterized by a specific cognitive profile frequently associating poor mathematical achievement, low spatial skills and reduced STM abilities. In order to identify the influence of visuo-spatial and STM processing on numerical magnitude abilities, twenty female participants with TS and twenty control female participants matched for verbal IQ and education level were administered a series of magnitude comparison tasks.

The heterogeneity of verbal short-term memory impairment in aphasia.

Verbal short-term memory (STM) impairment represents a frequent and long-lasting deficit in aphasia, and it will prevent patients from recovering fully functional language abilities. The aim of this study was to obtain a more precise understanding of the nature of verbal STM impairment in aphasia, by determining whether verbal STM impairment is merely a consequence of underlying language impairment, as suggested by linguistic accounts of verbal STM, or whether verbal STM impairment reflects an additional, specific deficit. We investigated this question by contrasting item-based STM measures, supposed to depend strongly upon language activation, and order-based STM measures, supposed to reflect the operation of specific, serial order maintenance mechanisms, in a sample of patients with single-word processing deficits at the phonological and/or lexical level.

Working Memory for Serial Order Is Dysfunctional in Adults With a History of Developmental Dyscalculia: Evidence From Behavioral and Neuroimaging Data.

Recent studies suggest that order working memory (WM) may be specifically associated with numerical abilities. This study explored behavioral performance and neural networks associated with verbal WM in adults with a history of developmental dyscalculia (DD). The DD group performed significantly poorer but with the same precision than the control group in order WM tasks and showed a lower activation of the right middle frontal gyrus during the order WM and the alphabetical order judgment tasks.

Working memory deficits in developmental dyscalculia: The importance of serial order.

Although a number of studies suggests a link between working memory (WM) storage capacity of short-term memory and calculation abilities, the nature of verbal WM deficits in children with developmental dyscalculia (DD) remains poorly understood. We explored verbal WM capacity in DD by focusing on the distinction between memory for item information (the items to be retained) and memory for order information (the order of the items within a list). We hypothesized that WM for order could be specifically related to impaired numerical abilities given that recent studies suggest close interactions between the representation of order information in WM and ordinal numerical processing.

The relationship between working memory for serial order and numerical development: a longitudinal study.

Despite numerous studies, the link between verbal working memory (WM) and calculation abilities remains poorly understood. The present longitudinal study focuses specifically on the role of serial order retention capacities, based on recent findings suggesting a link between ordinal processing in verbal WM and numerical processing tasks. Children were tested when they were in 3rd-year kindergarten (Time 1 [T1]), 1st grade (Time 2 [T2]), and 2nd grade of primary school (Time 3 [T3]), with WM tasks maximizing retention of serial order or item information, as well as with numerical judgment and calculation tasks.

Common neural substrates for ordinal representation in short-term memory, numerical and alphabetical cognition.

The representation and maintenance of serial order information is one of the main functions of verbal short-term memory (STM) but its neural correlates remain poorly understood. We show here that the neural substrates allowing for coding of order information in STM are shared with those supporting ordinal processing in the numerical and alphabetical domains. We designed an fMRI experiment determining the neural substrates sensitive to ordinal distance effects in numerical judgment, alphabetical judgment and serial order STM tasks.

The importance of encoding-related neural dynamics in the prediction of inter-individual differences in verbal working memory performance.

Studies of brain-behaviour interactions in the field of working memory (WM) have associated WM success with activation of a fronto-parietal network during the maintenance stage, and this mainly for visuo-spatial WM. Using an inter-individual differences approach, we demonstrate here the equal importance of neural dynamics during the encoding stage, and this in the context of verbal WM tasks which are characterized by encoding phases of long duration and sustained attentional demands. Participants encoded and maintained 5-word lists, half of them containing an unexpected word intended to disturb WM encoding and associated task-related attention processes.

Attention supports verbal short-term memory via competition between dorsal and ventral attention networks.

Interactions between the neural correlates of short-term memory (STM) and attention have been actively studied in the visual STM domain but much less in the verbal STM domain. Here we show that the same attention mechanisms that have been shown to shape the neural networks of visual STM also shape those of verbal STM. Based on previous research in visual STM, we contrasted the involvement of a dorsal attention network centered on the intraparietal sulcus supporting task-related attention and a ventral attention network centered on the temporoparietal junction supporting stimulus-related attention.