Anti-inflammatory and ulcerogenic effects of indomethacin and tenoxicam in combination with cimetidine.

Non-steroidal anti-inflammatory drugs (NSAIDs) have been widely used for the modulation of the inflammatory response. However, a number of facts involving the occurrence of gastrointestinal lesions have limited the chronic use of NSAIDs. In order to diminish the occurrence of gastrointestinal damage caused by NSAIDs, the combination of NSAIDs with the H2 receptor blocker, cimetidine, has been evaluated.

Use of licit and illicit drugs at the University of Alfenas.

Unlabelled: This paper reports the study of drug consumption carried out within the population of undergraduate students from 2 colleges of Alfenas, in the state of Minas Gerais state. Both licit and illicit drugs were studied, including alcohol, tobacco, marijuana, cocaine, heroin, crack, inhalants, glue, tranquilizers, stimulants, and others.

Methodology: The research included a wide bibliographical search and the application of a questionnaire to approximately 23% of the students (total of 6500 students).

Toxicity of a subchronic treatment with hydroalcoholic crude extract from Solanum grandiflorum (Ruiz et Pav) in rats.

The toxic effect of the hydroalcoholic crude extract (HACE) from the fruits of the Solanum grandiflorum was evaluated following subchronic treatment (p.o.) in Wistar rats for 65 days using the dose of 2 mg/kg.