Publications by authors named "Luciana-Estevam Simonato"

Objective: To investigate the performance of ChatGPT in the differential diagnosis of oral and maxillofacial diseases.

Methods: Thirty-seven oral and maxillofacial lesions findings were presented to ChatGPT-3.5 and - 4, 18 dental surgeons trained in oral medicine/pathology (OMP), 23 general dental surgeons (DDS), and 16 dental students (DS) for differential diagnosis.

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  • The case involves a 76-year-old male who received multiple endodontic treatments for a misdiagnosed glandular odontogenic cyst, which was initially mistaken for an inflammatory periapical lesion.
  • Glandular odontogenic cysts are known to be more aggressive compared to other types, and there's a lack of extensive research on this in older dental patients.
  • The correct diagnosis was confirmed through a biopsy, leading to successful surgery while ensuring the base of the mandible was preserved, emphasizing the need for careful diagnosis in elderly patients.
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  • A case study of a 16-year-old girl with a four-year-old nodule on her tongue illustrates the tumor's characteristics, which included myxoid and chondroid features confirmed through surgical excision and histopathological analysis.
  • The tumor's immunohistochemical markers (GFAP and S-100 proteins) helped confirm the diagnosis, and after five years, the patient showed no signs of tumor recurrence, highlighting the importance of recognizing this distinctive tumor to prevent misdiagnosis.
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  • * A case study of an 11-year-old girl with NBCCS showed she had several OKCs, but her scans of the chest and brain were normal, and her dental structure indicated some jaw alignment issues.
  • * The treatment involved a careful plan that included a combination of procedures to minimize surgery and the chance of the cysts returning, which proved successful as she showed no recurrence or new cysts over a 32-month follow-up.
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  • DISR is a drug-induced condition resembling sarcoidosis, linked to certain medications, including TNF-α antagonists.
  • A case study of a 49-year-old woman with Crohn's Disease treated with adalimumab shows ulcerated swelling in the oral area, diagnosed with granulomas via biopsy.
  • It's important to recognize DISR in patients on anti-TNF-α therapy when evaluating oral granulomatous lesions to ensure proper diagnosis and management.
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  • Brazil has a rich diversity of medicinal plants and long-standing traditional knowledge about their therapeutic uses, especially in ethnic communities.
  • The study tested hydroalcoholic extracts from rosemary, citronella, rue, neem, and lemon against various isolated fungi found in a daycare center in São Paulo.
  • Results indicated that rue, citronella, and lemon extracts were effective at low concentrations, showcasing the potential antifungal properties of these medicinal plants.
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Background Thoracic duct (TD) anomaly can be quite variable and dangerous in surgical interventions in the neck region as there are numerous variations in its formation and topography. This highlights the importance of full knowledge about the TD and its anatomical variations. Thus, it is important to emphasize that the lack of anatomical-clinical knowledge or surgical skill during an intervention can significantly hamper successful results.

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Garlic is one of the most common medicinal plants used since ancient times to treat diverse diseases within several cultures worldwide. Nevertheless, this plant has the potential to cause chemical burns of the skin and mucosa. This report presents a case of a garlic burn in the palate of a 57-year-old woman who applied garlic to the palate to relieve the pain of trigeminal neuralgia.

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Medication-related osteonecrosis of the jaw (MRONJ) results in progressive destruction of the jawbones, and advanced cases demand surgical intervention. The total removal of necrotic bone is required to prevent recurrence and infection. However, determining the limits between necrotic and healthy bone is a challenge.

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The early diagnosis of oral squamous cell carcinoma (OSCC) and oral potentially malignant disorders (OPMD) is challenging. The use of fluorescence visualization (FV) has been improved as an auxiliary method to early detect alterations in the oral mucosa suggestive of malignancy or pre-malignancy. However, perhaps due to some misinterpretation regarding the clinical purpose of this method, its applicability may have been underestimated.

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  • Lichen sclerosus is a rare long-term inflammatory condition, not commonly seen in the mouth.
  • It was identified in a 12-year-old girl, leading to damage of her gums.
  • After confirming the diagnosis with lab tests, she received corticosteroid injections, which effectively improved her symptoms.
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Background: Scientific literature shows the great potential of fluorescence visualization (FV) in the detection of lesions in the skin and mucosa, though its use has been intermitant. Thus, the aim of this study was to compare the detection of oral cancer and oral potentially malignant disorders (OPMD) with and without the use of fluorescence visualization in population screening.

Patients And Methods: During a population screening for oral cancer and OPMD, general practice dentists (GPD) performed conventional oral examination (COE) in the first year, and in the second year the FV was inserted in the oral examination.

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Validation studies of whole slide imaging (WSI) systems produce evidence regarding digital microscopy (DM). This systematic review aimed to provide information about the performance of WSI devices by evaluating intraobserver agreement reported in previously published studies as the best evidence to elucidate whether DM is reliable for primary diagnostic purposes. In addition, this review delineates the reasons for the occurrence of discordant diagnoses.

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Introduction: Malignant metastases to the oral cavity are rare and metastatic melanomas of the tongue are considered exceptionally uncommon, with less than 10 cases published in the English literature so far.

Case Reports: Two female patients in the 7th decade of life presented to our dental service with nodules in the tongue. Both patients had multiple metastases at the time of oral diagnosis and primary melanoma originated on the skin.

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Although head and neck squamous cell carcinoma represents one of the most common cancers among adults, it is rare in pediatric patients. The purpose of this report is to discuss the case of a 15-year-old male patient referred by his dentist due to a three-month old ulcer in his lower lip. The patient denied tobacco smoking and drinking alcohol, and confirmed that he performed manual labor in a brick yard, being exposed daily to the sun without protection.

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Background: To analyze the efficacy of fluorescence visualization in early detection of oral early neoplastic processes when used by an inexperienced and an adept oral examiner.

Methods: A dental student and an expert professional in oral diagnosis examined 15 randomly selected patients using conventional oral examination and fluorescence visualization searching for early signs of epithelial dysplasia and oral potentially malignant disorders. Patients detected with oral lesions in any of examinations were submitted to incisional biopsy for definitive diagnosis.

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Objective: The purpose of this study was to provide information regarding the marginal adaptation of composite resin onlays in primary teeth previously treated with 1% sodium hypochlorite (NaOCl) (pulp irrigant) using two different resin luting agents.

Material And Methods: Forty extracted sound primary molars had their crowns prepared in a standardized machine and were randomly divided into 4 groups (n=10): G1 (1% NaOCl irrigation+EnForce); G2 (EnForce); G3 (1% NaOCl irrigation+Rely X); G4 (Rely X). The onlays were made with Z250 composite resin on plaster models.

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  • - Osteosarcoma is a rare but aggressive cancer mainly affecting long bones in young adults, and when it appears in the head and neck, it typically has a poor prognosis.
  • - The article details a case of a young woman with chondroblastic osteosarcoma in her maxilla and maxillary sinus, discovered during a post-orthodontic check-up.
  • - It emphasizes the critical need for thorough oral exams in dental practices to catch such serious conditions early on.
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