Inflammatory cytokines and chemokines in obese adolescents with antibody against to adenovirus 36.

Obesity in adolescents has reached epidemic proportions and is associated with the inflammatory response and viral infections. The aim of this study was to understand the profile of inflammatory cytokines and chemokines associated with the inflammatory response and metabolic syndrome (MetS) in obese adolescents with positive serology for adenovirus 36 (ADV36). Thirty-six overweight, 36 obese, and 25 severe obesity adolescents aged 10 to 16 years were included in the study.

Excess body fat negatively affects bone mass in adolescents.

Objective: The aim of this study was to investigate the effects of excess body fat on bone mass in overweight, obese, and extremely obese adolescents.

Methods: This study included 377 adolescents of both sexes, ages 10 to 19 y. Weight, height, body mass index (BMI), bone age, bone mineral content (BMC), and bone mineral density (BMD) were obtained by dual-energy x-ray absorptiometry.

Metabolic syndrome reduces bone mineral density in overweight adolescents.

Growing concern has focused on the occurrence of metabolic syndrome (MetS) and its effects on bone mass. There is little information available in the literature concerning the relationship between MetS and BMD in adolescents. The aim of this study was to evaluate the effects of MetS and its components on bone mineral density (BMD) in overweight adolescent boys and girls.

Does excess weight interfere with bone mass accumulation during adolescence?

Obesity and osteoporosis are important global health problems characterized by increasing prevalence with high impact on morbidity and mortality. The objective of this review was to determine whether excess weight during adolescence interferes with bone mass accumulation. If bone mineral gain can be optimized during puberty, adults are less likely to suffer from the devastating complications of osteoporosis.