Publications by authors named "Luciana Mata da Silva"
Article Synopsis
- The study investigates the levels of various soluble immune mediators in gastric cancer (GC) patients compared to healthy controls, focusing on potential therapeutic targets for treatment.
- Results indicate low levels of sPD-1, sPD-L2, and sGal9, while levels of sPD-L1, sTIM-3, sGITR, and sGITRL were higher in GC patients, with variations based on cancer stages and specific tumor locations.
- Findings suggest a potential link between certain soluble mediators (sPD-1, sTIM-3, sGal9) and disease progression, as well as the association of low sGITR with increased mortality within the first
Background And Objectives: Previous studies have demonstrated that soluble forms of T-cell costimulatory molecules 4-1BB (s4-1BB) and OX40 (sOX40) interact with immune cells and may constitute a mechanism of immune evasion by tumors in various cancers. The role of the soluble forms of 4-1BB and OX40 in GC remains unclear. We aimed to examine the association between serum levels of s4-1BB and sOX40 and tumor progression in patients with GC.
View Article and Find Full Text PDFCancer risk-reducing surgery: Brazilian society of surgical oncology guideline part 1 (gynecology and breast).
Vandré Cabral Gomes Carneiro Ana Carolina Leite Vieira Costa Gifoni Benedito Mauro Rossi Carlos Eduardo Mattos da Cunha Andrade Fernanda Teresa de Lima Leonardo Silveira da Silva Barreto Luciana Mata da Silva Tyrone Cesar Silva Junior Walyson Silva Surimã
J Surg Oncol
July 2022
Article Synopsis
- Risk-reducing surgeries are key for managing hereditary cancer risks, significantly lowering the associated health issues and mortality.
- The Brazilian Society of Surgical Oncology developed guidelines to provide national standards for these surgical procedures.
- A team of experts reviewed literature and conducted discussions to create recommendations, achieving consensus on various risk-reduction surgeries like mastectomy and hysterectomy.