Computer-assisted methods to evaluate retinal vascular caliber: what are they measuring?

Purpose: Computer-assisted methods to measure retinal vessel diameters have been incorporated into research, but it is not clear which component of the vessels they are measuring. This study was conducted to compare measurements of retinal vessel diameter by using imaging-processing software on color fundus photographs (FPs) and fluorescein angiographs (FAs).

Methods: FP and FA images were taken simultaneously in 52 eyes of 31 patients referred for angiography for diagnosis of retinal disease.